Requin 300 mg/5 ml (Injection)
Unit Price: ৳ 10.20 (2 x 5: ৳ 102.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Quinine sulfate |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Uncomplicated, severe and complicated falciparum malaria
- Falciparum malaria resistant to other drugs
- Prevention of nocturnal muscle cramps
- Alleviation of muscle cramps in Thomsen's disease
Pharmacology
- Interference with protein metabolism
- Inhibition of nucleic acid synthesis in malarial parasites
- Highly active blood schizonticide
- Suppresses the asexual cycle of development of malaria parasites in the erythrocytes
Dosage & Administration
- Adult:
- Oral: 600 mg every 8 hours for 7 days
- Parenteral: Intravenous infusion - loading dose of 20 mg/kg, maintenance dose of 10 mg/kg every 8-12 hours
- Children:
- Oral: 10 mg/kg every 8 hours for 7 days
- Parenteral: Dosage calculated on a mg/kg basis
- Pregnancy: Safe for pregnant women
Contraindications
- Hypersensitivity reaction
- Optic neuritis
- Black water fever
Side Effects
- Cinchonism
- Tinnitus
- Headache
- Nausea
- Visual disturbances
- Hematological disorders
- Skin reactions
Pregnancy & Lactation
- Considered safe in pregnancy
- Excreted in breast milk in insignificant amount
Precautions & Warnings
- Severe heart disease
- Myasthenia gravis
- Diabetes mellitus
- Slow IV injection
- Potential side effects with Mefloquine
Therapeutic Class
- Anti-malarial drugs
Storage Conditions
Store at recommended conditions