Requin 300 mg (Tablet)
Unit Price: ৳ 3.44 (10 x 10: ৳ 344.00)
Strip Price: ৳ 34.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Quinine sulfate |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Uncomplicated falciparum malaria
- Severe falciparum malaria
- Complicated falciparum malaria
- Falciparum malaria resistant to other drugs
- Prevention of nocturnal muscle cramps
- Alleviation of muscle cramps in Thomsen's disease
Pharmacology
- Interference with protein metabolism
- Inhibition of nucleic acid synthesis in malarial parasites
- Highly active blood schizonticide
- Suppression of asexual cycle of malaria parasites in erythrocytes
Dosage & Administration
- Adult:
- Oral dosage: 600 mg (of quinine salt) every 8 hours for 7 days
- Parenteral dosage: Intravenous infusion of quinine
- Children:
- Oral dosage: 10 mg/kg every 8 hours for 7 days
- Parenteral dosage: Intravenous infusion calculated on a mg/kg basis
- Pregnancy: Safe for pregnant women
Contraindications
- Hypersensitivity reaction
- Optic neuritis
- Black water fever
Side Effects
- Cinchonism (tinnitus, headache, nausea, visual disturbances)
- Hematological disorders
- Skin reactions
Pregnancy & Lactation
Considered safe for therapeutic use in pregnancy, excreted in breast milk in insignificant amount
Precautions & Warnings
- Severe heart disease
- Myasthenia gravis
- Diabetes mellitus
- Slow IV injection
- Use of Mefloquine with Requin sulfate may increase side effects
Therapeutic Class
Anti-malarial drugs
Storage Conditions
Mefloquine use with Requin sulfate may increase side effects