Rabnil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Benham pharmaceuticals ltd
Also available as
Rabnil mups 20 mg tablet

Title

Rabnil Gastro-resistant Tablets

Categories

  • Medicine
  • Gastroenterology
  • Pharmacology
  • Proton Pump Inhibitor

Description

Rabnil Gastro-resistant tablets are indicated for the treatment of Active duodenal ulcer, Active benign gastric ulcer, Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD), Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance), Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD), Zollinger-Ellison Syndrome, and In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease.

Dimensions

Tablet size: standard

Color options

Not applicable

Functions

  • Suppresses gastric acid secretion
  • Inhibits the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell
  • Eradicates Helicobacter pylori

Materials

Not applicable

Technical specifications

  • Dosage:
    • Active Duodenal Ulcer and Active Benign Gastric Ulcer: 20 mg to be taken once daily in the morning
    • Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD): 20 mg to be taken once daily for four to eight weeks
    • Gastro-Esophageal Reflux Disease Long-term Management (GERD Maintenance): 20 mg or 10 mg once daily
    • Symptomatic treatment of moderate to very severe Gastro-Esophageal Reflux Disease (symptomatic GERD): 10 mg once daily
    • Treatment of GERD in pediatric patients 1 to 11 years of age (Less than 15 kg): 5 mg once daily for 12 weeks
    • Treatment of GERD in pediatric patients 1 to 11 years of age (15 kg or more): 10 mg once daily for 12 weeks
    • Zollinger-Ellison Syndrome: 60 mg once a day, may increase to 120 mg/day based on individual patient needs
    • Eradication of H. pylori: 20 mg twice daily for 7 days
  • Administration: Should be taken in the morning, before eating, and swallowed whole

Design elements

Gastro-resistant coating

Usability features

  • Well-tolerated in both short-term and long-term studies
  • Once-daily treatment
  • Long-term management option

Pharmacology

  • Mode of Action: Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase
  • Interaction:
    • May interact with compounds whose absorption is pH dependent
    • May result in a significant decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole
    • No interaction with liquid antacids observed
    • Atazanavir absorption is pH-dependent, so co-administration is not recommended
  • Contraindications:
    • Hypersensitivity to the active substance or excipients
    • Contra-indicated in pregnancy and during breastfeeding
  • Side Effects: May cause headache, diarrhea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, dizziness

Pregnancy and lactation

  • Pregnancy Category: US FDA pregnancy category 'C'
  • Lactation: May be excreted in human milk

Precautions and warnings

  • Symptomatic response to therapy does not preclude the presence of gastric or esophageal malignancy
  • Regular surveillance for long-term treatment
  • May increase the risk of hip, wrist and spine fracture, especially in the elderly or in presence of other recognized risk factors
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitor or substituted benzimidazoles
  • Blood dyscrasias and hepatic enzyme abnormalities have been reported
  • Severe hypomagnesemia and influence on vitamin B12 absorption
  • Association with subacute cutaneous lupus erythematosus (SCLE)
  • Interference with laboratory tests (CgA)

Special populations

  • Renal and Hepatic Impairment: No dosage adjustment necessary
  • Pediatric Populations: Not recommended for use due to lack of data on safety and efficacy

Overdose effects

Effects are generally minimal and reversible without further medical intervention, no specific antidote known

Storage conditions

Keep below 30°C temperature, away from light & moisture

Chemical structure

  • Molecular Formula: C18H21N3O3S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-942-rabeprazole-sodium-chemical-structure-atwg0Q4PlndQZhOY9GHX.svg

Common questions

  • What is Rabnil 20 mg Capsule?: A proton pump inhibitor (PPI) that suppresses gastric acid secretion
  • What is Rabnil 20 mg Capsule used for?: Treating Duodenal ulcer, Gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
  • What are the side effects of Rabnil 20 mg Capsule?: Headache, diarrhea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, dizziness
  • How should I take Rabnil 20 mg Capsule?: Should be taken with food, usual dose is one tablet once a day, do not exceed prescribed dose
  • Can I take Rabnil 20 mg Capsule while pregnant or breastfeeding?: Not recommended for use during pregnancy or breastfeeding, talk to your doctor
  • What should I do if I overdose on Rabnil 20 mg Capsule?: Call your doctor or the Poison Control Center immediately
  • How long should I take Rabnil 20 mg Capsule?: Length of treatment depends on the condition being treated
  • Is there anything else I should know about Rabnil 20 mg Capsule?: Can cause dry mouth and constipation, and may lead to bone problems and calcium deficiency if used long-term

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