Rmax 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Delta pharma ltd

Brand Name

  • Rmax

Therapeutic Class

  • Proton Pump Inhibitor

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

  • Active Duodenal Ulcer and Active Benign Gastric Ulcer: 20 mg once daily in the morning
  • Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD): 20 mg once daily for four to eight weeks
  • Gastro-Esophageal Reflux Disease Long-term Management (GERD Maintenance):
    • 20 mg once daily
    • 10 mg once daily based on patient response
  • Symptomatic treatment of moderate to very severe Gastro-Esophageal Reflux Disease (symptomatic GERD):
    • 10 mg once daily
    • 10 mg once daily on-demand when needed
  • Treatment of GERD in pediatric patients 1 to 11 years of age (Less than 15 kg): 5 mg once daily for 12 weeks
  • Treatment of GERD in pediatric patients 1 to 11 years of age (15 kg or more): 10 mg once daily for 12 weeks
  • Zollinger-Ellison Syndrome:
    • 60 mg once daily
    • titrated upwards to 120 mg/day based on individual patient needs
  • Eradication of H. pylori: Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily and amoxicillin 1g twice daily for 7 days

Administration

Should be taken in the morning, before eating, and should not be chewed or crushed, but swallowed whole.

Interactions

  • Positive Interaction: No interaction with liquid antacids was observed.
  • Negative Interaction: Co-administration with ketoconazole or itraconazole may result in a significant decrease in antifungal plasma levels.

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'. Should not be used during pregnancy or breastfeeding without medical advice.

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric or esophageal malignancy
  • Proton pump inhibitors may modestly increase the risk of hip, wrist, and spine fracture
  • Cross-hypersensitivity reactions with other proton pump inhibitors or substituted benzimidazoles cannot be excluded
  • Hypomagnesaemia and its symptoms should be monitored in long-term users
  • May reduce the absorption of vitamin B12

Use in Special Populations

  • No dosage adjustment is necessary for patients with renal or hepatic impairment
  • Not recommended for use in children due to a lack of data on safety and efficacy

Overdose Effects

  • Maximum Established Exposure: 60 mg twice daily, or 160 mg once daily
  • Effects: Generally minimal, representative of the known adverse event profile and reversible without further medical intervention
  • Antidote: No specific antidote known. Symptomatic and general supportive measures should be utilized.

Storage Conditions

Keep below 30°C temperature, away from light & moisture, and out of the reach of children.

Chemical Structure

  • Molecular Formula: C18H21N3O3S

Common Questions

  • What is Rmax 20 mg Capsule?: A proton pump inhibitor (PPI) that suppresses gastric acid secretion.
  • What is Rmax 20 mg Capsule used for?: To treat Duodenal ulcer, Gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
  • What are the side effects of Rmax 20 mg Capsule?: Common side effects include diarrhea, constipation, nausea, and vomiting. Serious side effects are rare but can include kidney problems, liver damage, and bone fractures.
  • How should I take Rmax 20 mg Capsule?: Should be taken with food. The usual dose is one tablet once a day. Do not take more than the prescribed dose.
  • Can I take Rmax 20 mg Capsule while pregnant or breastfeeding?: Not recommended for use during pregnancy or breastfeeding. Consult a doctor for advice.
  • What should I do if I overdose on Rmax 20 mg Capsule?: Call your doctor or the Poison Control Center immediately. Overdose can cause symptoms such as drowsiness, confusion, and seizures.
  • How long should I take Rmax 20 mg Capsule?: The length of time depends on the condition being treated. Consult your doctor for guidance.
  • Is there anything else I should know about Rmax 20 mg Capsule?: Can cause dry mouth and constipation. Long-term use can cause weak bones and a deficiency of minerals such as magnesium.

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