E-Reb 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Ethical drugs limited

Indications

  • Treatment of active duodenal ulcer
  • Treatment of active benign gastric ulcer
  • Symptomatic treatment of erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Long-term management of gastro-esophageal reflux disease (GERD)
  • Symptomatic treatment of moderate to very severe GERD
  • Treatment of Zollinger-Ellison Syndrome
  • In combination with antibacterial therapy for Helicobacter pylori eradication

Pharmacology

  • Suppresses gastric acid secretion
  • Inhibits the gastric H+/K+-ATPase
  • Characterized as a gastric proton-pump inhibitor

Dosage

  • 20 mg once daily for active duodenal ulcer and active benign gastric ulcer
  • 20 mg once daily for four to eight weeks for erosive or ulcerative GERD
  • Maintenance dose of 20 mg or 10 mg once daily for long-term management of GERD
  • 10 mg once daily for symptomatic treatment of moderate to very severe GERD
  • 5 mg or 10 mg once daily for 12 weeks for pediatric GERD treatment
  • Starting dose of 60 mg once daily for Zollinger-Ellison Syndrome with potential titration to 120 mg/day
  • Combination therapy for H. pylori eradication

Administration

  • Take in the morning before eating
  • Tablets should be swallowed whole

Interaction

  • Potential interaction with pH-dependent compounds like ketoconazole or itraconazole
  • No interaction with liquid antacids observed
  • Atazanavir absorption is pH-dependent and should not be co-administered with rabeprazole

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

  • US FDA pregnancy category 'C'
  • No adequate and well-controlled studies in pregnant women

Precautions & Warnings

  • Symptomatic response does not exclude malignancy
  • Regular surveillance for long-term treatment
  • Possible increase in risk of hip, wrist and spine fracture with long-term high-dose use
  • Risk of cross-hypersensitivity reactions

Use in Special Populations

  • No dosage adjustment for renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

  • Maximum established exposure
  • Generally minimal effects
  • Reversible without further medical intervention
  • No specific antidote

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H21N3O3S

Common Questions

  • What is E-Reb 20 mg Tablet?
  • What is E-Reb 20 mg Tablet used for?
  • What are the side effects of E-Reb 20 mg Tablet?
  • How should I take E-Reb 20 mg Tablet?
  • Can I take E-Reb 20 mg Tablet while pregnant or breastfeeding?
  • What should I do if I overdose on E-Reb 20 mg Tablet?
  • How long should I take E-Reb 20 mg Tablet?
  • Is there anything else I should know about E-Reb 20 mg Tablet?
  • Does E-Reb 20 mg Tablet cause bone problems?
  • Can I take E-Reb 20 mg Tablet with vitamin D?

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