RP-20 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 6.90 (5 x 10: ৳ 345.00)
Strip Price: ৳ 69.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rabeprazole sodium |
| Company | Globe pharmaceuticals ltd |
Title
- RP-20 Gastro-resistant Tablets
Categories
- Medicine
- Pharmaceuticals
- Health & Wellness
Description
- Indicated for the treatment of active duodenal ulcer, active benign gastric ulcer, symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD), Zollinger-Ellison Syndrome, and in combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease
- Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell
- The recommended oral dose for active duodenal ulcer and active benign gastric ulcer is 20 mg once daily in the morning. Most patients with active duodenal ulcer heal within four weeks. Most patients with active benign gastric ulcer heal within six weeks
Dosage Instructions
- 20 mg to be taken once daily in the morning
- 20 mg to be taken once daily for four to eight weeks
- Maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily
Symptomatic Treatment
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
Pediatric Dosage
- 5 mg once daily for pediatric patients 1 to 11 years of age (Less than 15 kg)
- 10 mg once daily for pediatric patients 1 to 11 years of age (15 kg or more)
Zollinger-Ellison Syndrome Dosage
- Recommended adult starting dose is 60 mg once a day
Eradication of H. pylori Dosage
- Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily and amoxicillin 1g twice daily for 7 days
Administration
Rabeprazole tablets should be taken in the morning, before eating and should not be chewed or crushed, but should be swallowed whole
Interactions
- Co-administration with ketoconazole or itraconazole may result in a significant decrease in antifungal plasma levels
- No interaction with liquid antacids was observed
- PPIs, including rabeprazole, should not be co-administered with atazanavir
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Contra-indicated in pregnancy and during breastfeeding
Side Effects
- Headache
- Diarrhoea
- Abdominal pain
- Vomiting
- Constipation
- Dry mouth
- Increased or decreased appetite
- Muscle pain
- Drowsiness
- Dizziness
Pregnancy Category
US FDA pregnancy category 'C'
Precautions & Warnings
- Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy
- Patients on long-term treatment should be kept under regular surveillance
- May modestly increase the risk of hip, wrist and spine fracture, predominantly in the elderly or in presence of other recognised risk factors
- A risk of cross-hypersensitivity reactions with other proton pump inhibitor or substituted benzimidazoles cannot be excluded
- Severe hypomagnesaemia has been reported in patients treated with PPIs like rabeprazole for at least three months
Use in Special Populations
- No dosage adjustment is necessary for patients with renal or hepatic impairment
- Not recommended for use in children due to a lack of data on safety and efficacy
Overdose Effects
Minimal, reversible without further medical intervention. RP-20 is extensively protein bound and is, therefore, not dialysable
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H21N3O3S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-942-rabeprazole-sodium-chemical-structure-atwg0Q4PlndQZhOY9GHX.svg
Common Questions
- What is RP-20 20 mg Tablet and its uses?
- What are the side effects of RP-20 20 mg Tablet?
- How should I take RP-20 20 mg Tablet?
- Can I take RP-20 20 mg Tablet while pregnant or breastfeeding?
- What should I do if I overdose on RP-20 20 mg Tablet?
- How long should I take RP-20 20 mg Tablet?
- Is there anything else I should know about RP-20 20 mg Tablet?
- Does RP-20 20 mg Tablet cause bone problems?
- Can I take RP-20 20 mg Tablet with vitamin D?
- Quick Tips: It is a well-tolerated medicine and provides relief for a long time.