Rasonix JR 10 mg (Sprinkle Capsule)
Unit Price: ৳ 3.50 (7 x 8: ৳ 196.00)
Strip Price: ৳ 28.00
Medicine Details
Category | Details |
---|---|
Generic | Rabeprazole sodium |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Active duodenal ulcer
- Active benign gastric ulcer
- Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
- Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease
- Zollinger-Ellison Syndrome
- Combination therapy for eradication of Helicobacter pylori
Pharmacology
- Suppression of gastric acid secretion
- Inhibition of H+/K+-ATPase
- Classification as a gastric proton-pump inhibitor
Dosage
- Recommended oral dose for active duodenal ulcer and active benign gastric ulcer
- Recommended oral dose for erosive or ulcerative GERD
- Maintenance dose for long-term GERD management
- Symptomatic treatment dose for moderate to severe GERD
- Pediatric dose for GERD
- Recommended dose for Zollinger-Ellison Syndrome
- Recommended eradication therapy dose for H. pylori
Administration
- Morning intake before eating
- Caution against chewing or crushing the tablet
- Swallowing the tablet whole
Interaction
- Potential interaction with pH-dependent absorption compounds
- Co-administration with ketoconazole or itraconazole leading to decreased plasma levels
- No interaction with liquid antacids
- pH-dependent absorption interference with atazanavir
Contraindications
- Hypersensitivity to active substance or excipients
- Contra-indicated in pregnancy and during breastfeeding
Side Effects
- Headache
- Diarrhoea
- Abdominal pain
- Vomiting
- Constipation
- Dry mouth
- Increased or decreased appetite
- Muscle pain
- Drowsiness
- Dizziness
Pregnancy & Lactation
- US FDA pregnancy category 'C'
- No adequate and well-controlled studies in pregnant women
- Potential excretion in human milk
Precautions & Warnings
- Exclusion of malignancy prior to treatment
- Regular surveillance for long-term treatment
- Modestly increased risk of fractures with long-term use
- Risk of cross-hypersensitivity reactions
- Caution against chewing or crushing the tablet
- Reports of blood dyscrasias and hepatic enzyme abnormalities
- Special consideration for patients with hepatic impairment
- Co-administration not recommended with atazanavir
- Possible increased risk of gastrointestinal infections
- Risk of severe hypomagnesemia after prolonged treatment
- Potential reduction in vitamin B12 absorption
- Association with subacute cutaneous lupus erythematosus (SCLE)
- Interference with laboratory tests
Use in Special Populations
- No dosage adjustment needed for renal or hepatic impairment
- Not recommended for use in children
Overdose Effects
- Maximum established exposure
- Minimal effects representative of known adverse event profile
- Reversible without further medical intervention
- No specific antidote known
- Extensive protein binding
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H21N3O3S
Common Questions
- Description of Rasonix JR 10 mg Capsule
- Use of Rasonix JR 10 mg Capsule
- Side effects of Rasonix JR 10 mg Capsule
- Administration of Rasonix JR 10 mg Capsule
- Safety of Rasonix JR 10 mg Capsule during pregnancy or breastfeeding
- Actions to take in case of overdose with Rasonix JR 10 mg Capsule
- Duration of treatment with Rasonix JR 10 mg Capsule
- Additional information about Rasonix JR 10 mg Capsule
- Potential bone-related issues with Rasonix JR 10 mg Capsule
- Co-administration of Rasonix JR 10 mg Capsule with vitamin D
- Quick tips for using Rasonix JR 10 mg Capsule
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