Rabetac 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (6 x 10: ৳ 480.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Navana pharmaceuticals ltd
Also available as
Rabetac 20 mg tablet

Title

  • Rabetac 20 mg Capsule

Categories

  • Gastrointestinal Medicine
  • Proton Pump Inhibitor

Indications

  • Active Duodenal Ulcer
  • Active Benign Gastric Ulcer
  • Symptomatic Erosive or Ulcerative Gastro-esophageal Reflux Disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe Gastro-esophageal Reflux Disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Mode of Action

  • Suppresses gastric acid secretion
  • Inhibits the gastric H+/K+-ATPase

Dosage

  • 20 mg recommended oral dose for active duodenal ulcer and active benign gastric ulcer
  • 20 mg recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • 20 mg or 10 mg maintenance dose for GERD long-term management
  • 10 mg recommended oral dose for symptomatic treatment of moderate to very severe GERD
  • 5 mg once daily for pediatric patients 1 to 11 years of age (Less than 15 kg)
  • 10 mg once daily for pediatric patients 1 to 11 years of age (15 kg or more)
  • 60 mg once daily recommended adult starting dose for Zollinger-Ellison Syndrome
  • Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for H. pylori eradication

Administration

  • To be taken in the morning before eating

Interaction

  • May interact with compounds whose absorption is pH dependent
  • Co-administration with ketoconazole or itraconazole may decrease antifungal plasma levels
  • No interaction with liquid antacids observed
  • Absorption of atazanavir is pH-dependent, should not be co-administered with PPIs

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

  • US FDA pregnancy category 'C'
  • No adequate and well-controlled studies in pregnant women
  • Likely to be excreted in human milk

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric or esophageal malignancy
  • Regular surveillance for long-term treatment
  • May modestly increase the risk of hip, wrist, and spine fracture
  • Risk of cross-hypersensitivity reactions with other PPIs
  • Hypomagnesaemia risk
  • Influence on vitamin B12 absorption
  • Association with subacute cutaneous lupus erythematosus (SCLE)
  • Interference with laboratory tests

Use in Special Populations

  • No dosage adjustment is necessary for patients with renal or hepatic impairment
  • Not recommended for use in children due to a lack of data on safety and efficacy

Overdose Effects

  • Maximum established exposure not exceeded 60 mg twice daily or 160 mg once daily
  • Generally minimal effects, reversible without further medical intervention
  • No specific antidote known
  • Not dialysable

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep below 30°C temperature, away from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H21N3O3S

Common Questions and Answers

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