Serelose 3.35 gm/5 ml (Oral Solution)

100 ml bottle: ৳ 130.00

Medicine Details

Category Details
Generic Lactulose
Company Beximco pharmaceuticals ltd

Title

  • Serelose 3.35 gm/5 ml Oral Solution

Categories

  • Medicine
  • Laxative
  • Hyperosmolar Laxative
  • Osmotic Purgatives

Description

  • Effective treatment approach for constipation
  • Non-absorbable disaccharide
  • Draws water into the bowel
  • Promotes soft stool
  • Accelerates bowel motion

Indications

  • Treatment of chronic constipation
  • Intestinal flora disturbances
  • Increased blood ammonia levelsin hepatopathy
  • Portal-systemic encephalopathy

Pharmacology

  • Synthetic disaccharide
  • Metabolized in the colon by saccharolytic bacteria
  • Produces low molecular weight organic acids
  • Lowers pH of colon contents
  • Promotes water retention
  • Increases peristaltic activity
  • Minimally absorbed

Dosage & Administration

  • Adults: 3-6 tea-spoons daily
  • Children up to 14 years: 3 tea-spoons daily
  • Infants and toddlers: 1-2 tea-spoons daily
  • For damaged intestinal flora: 1-2 tea-spoons daily
  • For reduction of blood ammonia level: maximum of 18-30 tea-spoons daily

Interaction

  • No significant drug interactions
  • Intensified glycosidic effect of cardiac glycosides by potassium deficiency in abuse

Contraindications

  • Hypersensitivity to galactose and/or lactose
  • Galactose-free diet
  • Gastro-cardial symptom complex
  • Suspected intestinal obstruction

Side Effects

  • Flatulence
  • Cramp
  • Abdominal discomfort
  • Overdose can result in diarrhoea
  • Loss of electrolytes, primarily potassium in abuse

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adverse effects reported
  • Use during pregnancy and lactation to be decided by registered physician

Precautions & Warnings

  • Administer with care to patients intolerant to lactulose
  • Consideration needed for diabetics in (pre) coma hepaticum treatment

Overdose Effects

  • No reports of accidental overdosage
  • Expected symptoms: diarrhoea and abdominal cramps

Therapeutic Class

  • Osmotic purgatives

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C12H22O11

Common Questions

  • Use for treating constipation
  • Frequency of use for constipation and liver disease
  • Time to see benefits of treatment
  • Mechanism as a laxative
  • Side effects
  • Recommended duration of use
  • Use in patients allergic to it or intolerant to lactose
  • Consequences of overdose

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