Profast 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Renata limited

Title

  • Profast 20 mg Gastro-resistant Tablet

Categories

  • Medicine
  • Gastrointestinal
  • Proton Pump Inhibitor

Description

  • Profast Gastro-resistant tablets are indicated for the treatment of active duodenal ulcer, active benign gastric ulcer, symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD), and more.
  • Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Indications

  • Treatment of active duodenal ulcer
  • Treatment of active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • Eradication of Helicobacter pylori in patients with peptic ulcer disease

Dosage

  • 20 mg to be taken once daily in the morning for active duodenal ulcer and active benign gastric ulcer
  • 20 mg to be taken once daily for four to eight weeks for erosive or ulcerative GERD
  • Rabeprazole sodium 20 mg or 10 mg once daily for GERD maintenance
  • 10 mg once daily for symptomatic treatment of moderate to very severe GERD
  • 60 mg once a day for Zollinger-Ellison Syndrome
  • Combination therapy for H. pylori eradication: Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for 7 days

Administration

  • Rabeprazole tablets should be taken in the morning, before eating, and swallowed whole

Interaction

  • Interaction with compounds whose absorption is pH dependent may occur
  • Co-administration of Profast with ketoconazole or itraconazole may result in a significant decrease in antifungal plasma levels
  • No interaction with liquid antacids observed
  • PPIs, including rabeprazole, should not be co-administered with atazanavir

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

  • US FDA pregnancy category 'C'
  • No adequate and well-controlled studies in pregnant women
  • Rabeprazole is likely to be excreted in human milk

Precautions & Warnings

  • Regular surveillance for patients on long-term treatment
  • Possible increase in the risk of hip, wrist, and spine fracture with long-term high dose use
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitor or substituted benzimidazoles
  • Caution against chewing or crushing tablets
  • Reports of blood dyscrasias and hepatic enzyme abnormalities

Use in Special Populations

  • No dosage adjustment is necessary for patients with renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

  • Maximum established exposure has not exceeded 60 mg twice daily
  • Effects are generally minimal and reversible without further medical intervention
  • No specific antidote is known

Chemical Structure

  • Molecular Formula: C18H21N3O3S

Commonly Asked Questions

  • What is Profast 20 mg Tablet?
  • What is Profast 20 mg Tablet used for?
  • What are the side effects of Profast 20 mg Tablet?
  • How should I take Profast 20 mg Tablet?
  • Can I take Profast 20 mg Tablet while pregnant or breastfeeding?
  • What should I do if I overdose on Profast 20 mg Tablet?
  • How long should I take Profast 20 mg Tablet?
  • Is there anything else I should know about Profast 20 mg Tablet?
  • Does Profast 20 mg Tablet cause bone problems?
  • Can I take Profast 20 mg Tablet with vitamin D?
  • Quick Tips

Storage Conditions

  • Keep below 30°C temperature, away from light & moisture
  • Keep out of the reach of children

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