Respite 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.02 (5 x 10: ৳ 301.00)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Synovia pharma plc

Indications

  • Treatment of active duodenal ulcer
  • Treatment of active benign gastric ulcer
  • Treatment of symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Long-term management of gastro-esophageal reflux disease (GERD maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Treatment of Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

  • Suppression of gastric acid secretion
  • Inhibition of the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell
  • Characterized as a gastric proton-pump inhibitor

Dosage

  • Recommended oral doses for active duodenal ulcer and active benign gastric ulcer
  • Recommended oral dose for erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Recommended oral dose for GERD maintenance
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Treatment of GERD in pediatric patients 1 to 11 years of age
  • Treatment of Zollinger-Ellison Syndrome
  • Eradication of H. pylori
  • Duration of therapy for various conditions

Administration

  • Recommended time for taking the tablets
  • Instruction to swallow whole without chewing or crushing

Interaction

  • Potential interaction with compounds dependent on pH for absorption
  • Potential interaction with ketoconazole or itraconazole
  • No interaction with liquid antacids observed
  • Absorption of atazanavir is pH-dependent; caution advised in co-administration

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients
  • Contraindicated in pregnancy and during breastfeeding

Side Effects

  • Common side effects such as headache, diarrhea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, and dizziness

Pregnancy & Lactation

  • US FDA pregnancy category 'C'
  • Animal studies show no evidence of harm to the fetus
  • Decision making for nursing mothers

Precautions & Warnings

  • Possibility of malignancy should be excluded prior to commencing treatment
  • Regular surveillance for long-term treatment
  • Increased risk of hip, wrist, and spine fracture in long-term high-dose treatment especially in the elderly
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors or substituted benzimidazoles
  • Post marketing reports of blood dyscrasias and hepatic enzyme abnormalities

Use in Special Populations

  • No dosage adjustment needed for patients with renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

  • Maximum established exposure and known adverse event profile
  • Minimal and reversible effects without specific antidote
  • Not dialysable

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Temperature and environmental conditions for storage
  • Safety measures to keep out of reach of children

Chemical Structure

  • Molecular Formula : C18H21N3O3S
  • Visual representation of the chemical structure

Common Questions about Respite 20 mg Tablet

  • Overview of Respite 20 mg Tablet
  • Uses of Respite 20 mg Tablet
  • Common side effects of Respite 20 mg Tablet
  • Guidelines for taking Respite 20 mg Tablet
  • Safety considerations during pregnancy or breastfeeding
  • Actions in case of overdose
  • Duration of treatment
  • Additional information and quick tips

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