Sinalac 3.35 gm/5 ml (Oral Solution)

60 ml bottle: ৳ 70.00

Medicine Details

Category Details
Generic Lactulose
Company Ibn sina pharmaceuticals ltd

Indications

  • Treatment of chronic constipation
  • Management of intestinal flora disturbances
  • Reducing blood ammonia levels in hepatopathy
  • Alleviating symptoms of portal-systemic encephalopathy

Description

  • Hyperosmolar laxative
  • Effective treatment for constipation
  • Non-absorbable disaccharide
  • Promotes soft stool and accelerates bowel motion

Pharmacology

  • Synthetic disaccharide
  • Metabolized in the colon by saccharolytic bacteria
  • Produces low molecular weight organic acids
  • Lowers pH of colon contents
  • Promotes retention of water by osmotic effect
  • Increases peristaltic activity

Dosage & Administration

  • Adult dosage: 3-6 teaspoons daily (initially) and 1.5-6 teaspoons daily (long-term)
  • Children dosage: 3 teaspoons daily (initially) and 1-2 teaspoons daily (long-term)
  • Infant and toddler dosage: 1-2 teaspoons daily (initially) and 1 teaspoon daily (long-term)
  • Dosage for damaged intestinal flora: 1-2 teaspoons daily for adults and 1 teaspoon daily for children
  • Max dosage for hyper-ammoniemia in hepatopathy: 18-30 teaspoons daily

Interaction

  • No significant drug interactions
  • Glycosidic effect of cardiac glycosides can be intensified by potassium deficiency

Contraindications

  • Hypersensitivity to galactose or lactose
  • Galactose-free diet
  • Gastro-cardial symptom complex
  • Suspected intestinal obstruction

Side Effects

  • Occasional flatulence, cramp, and abdominal discomfort
  • Rapidly eliminated by reducing the dose
  • Overdose can result in diarrhea
  • Loss of electrolytes, primarily potassium in abuse

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adverse effects reported in studies

Precautions & Warnings

  • Administer with care to patients intolerant to Sinalac
  • Consider higher dose for treatment of (pre) coma hepaticum in diabetics

Overdose Effects

  • No reports of accidental overdosage
  • Expected symptoms: diarrhea and abdominal cramps

Therapeutic Class

  • Osmotic purgatives

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C12H22O11
  • Image of Chemical Structure

Common Questions

  • Use for treating constipation and reducing blood ammonia in liver disease
  • Frequency of use: once a day for constipation, three or four times a day for liver disease
  • Time to see benefits: 2-3 days
  • Main usage: treating infrequent bowel movements, hard and dry stools
  • Sinalac is a laxative that softens stools by pulling in water from the body to the large intestine
  • Common side effects: diarrhea, flatulence, nausea, vomiting, abdominal pain
  • Consult a doctor for advice on duration of use
  • Not to be given to patients allergic to it or intolerant to lactose
  • Potential effects of exceeding recommended dose: abdominal pain, electrolyte imbalance, diarrhea

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