Stogut 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.02 (6 x 10: ৳ 300.95)

Strip Price: ৳ 50.16

Medicine Details

Category	Details
Generic	Rabeprazole sodium
Company	United pharmaceuticals ltd

Indications

Active duodenal ulcer
Active benign gastric ulcer
Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
Zollinger-Ellison Syndrome
In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

20 mg to be taken once daily in the morning for active duodenal ulcer and active benign gastric ulcer
20 mg to be taken once daily for four to eight weeks for erosive or ulcerative gastro-esophageal reflux disease (GERD)
20 mg or 10 mg once daily for long-term management of GERD
10 mg once daily for symptomatic treatment of moderate to very severe GERD
5 mg once daily for pediatric patients 1 to 11 years of age (Less than 15 kg)
10 mg once daily for pediatric patients 1 to 11 years of age (15 kg or more)
60 mg once a day for Zollinger-Ellison Syndrome
Eradication therapy for H. pylori: Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for 7 days

Administration

Rabeprazole tablets should be taken in the morning, before eating, and swallowed whole without chewing or crushing.

Interaction

Potential interaction with compounds whose absorption is pH dependent
Possible decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole
No interaction with liquid antacids observed
Co-administration with atazanavir is not recommended

Contraindications

Hypersensitivity to the active substance or to any of the excipients
Contra-indicated in pregnancy and during breastfeeding

Side Effects

Headache
Diarrhoea
Abdominal pain
Vomiting
Constipation
Dry mouth
Increased or decreased appetite
Muscle pain
Drowsiness
Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'. Rabeprazole is likely to be excreted in human milk, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Precautions & Warnings

Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy
Patients on long-term treatment should be kept under regular surveillance
May modestly increase the risk of fracture, especially in the elderly or in presence of other recognised risk factors
Risk of cross-hypersensitivity reactions with other proton pump inhibitors
Caution in patients with hepatic impairment
Co-administration with atazanavir is not recommended
Possible increased risk of gastrointestinal infections
Severe hypomagnesaemia reported in patients treated with PPIs for at least three months
May reduce the absorption of vitamin B12
Associated with very infrequent cases of SCLE
Increased Chromogranin A (CgA) level may interfere with investigations for neuroendocrine tumours

Use in Special Populations

No dosage adjustment is necessary for patients with renal or hepatic impairment
Not recommended for use in children due to a lack of data on safety and efficacy

Overdose Effects

Effects are generally minimal, representative of the known adverse event profile and reversible without further medical intervention. No specific antidote is known.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Chemical Structure

Molecular Formula: C18H21N3O3S
Chemical Structure Image: URL

Common Questions about Stogut 20 mg Tablet

What is Stogut 20 mg Tablet?: A proton pump inhibitor (PPI) that suppresses gastric acid secretion
What is Stogut 20 mg Tablet used for?: Treatment of Duodenal ulcer, Gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
What are the side effects of Stogut 20 mg Tablet?:
- Diarrhea
- Constipation
- Nausea
- Vomiting
- Headache
- Dizziness
- Rash
- Dry mouth
- Kidney problems
- Liver damage
- Bone fractures
How should I take Stogut 20 mg Tablet?: Should be taken with food. The usual dose is one tablet once a day. Do not take more than the prescribed dose.
Can I take Stogut 20 mg Tablet while pregnant or breastfeeding?: Not recommended for use during pregnancy or breastfeeding. Risk and benefits should be discussed with a doctor.
What should I do if I overdose on Stogut 20 mg Tablet?: Call a doctor or the Poison Control Center immediately. Overdose symptoms can include drowsiness, confusion, and seizures.
How long should I take Stogut 20 mg Tablet?: The length of treatment will depend on the specific condition being treated.
Is there anything else I should know about Stogut 20 mg Tablet?: It can cause dry mouth and constipation. Long-term use can lead to weak bones and a deficiency of minerals such as magnesium.