Stogut 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.02 (6 x 10: ৳ 300.95)
Strip Price: ৳ 50.16

Medicine Details

Category Details
Generic Rabeprazole sodium
Company United pharmaceuticals ltd

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

  • 20 mg to be taken once daily in the morning for active duodenal ulcer and active benign gastric ulcer
  • 20 mg to be taken once daily for four to eight weeks for erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • 20 mg or 10 mg once daily for long-term management of GERD
  • 10 mg once daily for symptomatic treatment of moderate to very severe GERD
  • 5 mg once daily for pediatric patients 1 to 11 years of age (Less than 15 kg)
  • 10 mg once daily for pediatric patients 1 to 11 years of age (15 kg or more)
  • 60 mg once a day for Zollinger-Ellison Syndrome
  • Eradication therapy for H. pylori: Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for 7 days

Administration

Rabeprazole tablets should be taken in the morning, before eating, and swallowed whole without chewing or crushing.

Interaction

  • Potential interaction with compounds whose absorption is pH dependent
  • Possible decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole
  • No interaction with liquid antacids observed
  • Co-administration with atazanavir is not recommended

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'. Rabeprazole is likely to be excreted in human milk, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy
  • Patients on long-term treatment should be kept under regular surveillance
  • May modestly increase the risk of fracture, especially in the elderly or in presence of other recognised risk factors
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors
  • Caution in patients with hepatic impairment
  • Co-administration with atazanavir is not recommended
  • Possible increased risk of gastrointestinal infections
  • Severe hypomagnesaemia reported in patients treated with PPIs for at least three months
  • May reduce the absorption of vitamin B12
  • Associated with very infrequent cases of SCLE
  • Increased Chromogranin A (CgA) level may interfere with investigations for neuroendocrine tumours

Use in Special Populations

  • No dosage adjustment is necessary for patients with renal or hepatic impairment
  • Not recommended for use in children due to a lack of data on safety and efficacy

Overdose Effects

Effects are generally minimal, representative of the known adverse event profile and reversible without further medical intervention. No specific antidote is known.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C18H21N3O3S
  • Chemical Structure Image: URL

Common Questions about Stogut 20 mg Tablet

  • What is Stogut 20 mg Tablet?: A proton pump inhibitor (PPI) that suppresses gastric acid secretion
  • What is Stogut 20 mg Tablet used for?: Treatment of Duodenal ulcer, Gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
  • What are the side effects of Stogut 20 mg Tablet?:
    • Diarrhea
    • Constipation
    • Nausea
    • Vomiting
    • Headache
    • Dizziness
    • Rash
    • Dry mouth
    • Kidney problems
    • Liver damage
    • Bone fractures
  • How should I take Stogut 20 mg Tablet?: Should be taken with food. The usual dose is one tablet once a day. Do not take more than the prescribed dose.
  • Can I take Stogut 20 mg Tablet while pregnant or breastfeeding?: Not recommended for use during pregnancy or breastfeeding. Risk and benefits should be discussed with a doctor.
  • What should I do if I overdose on Stogut 20 mg Tablet?: Call a doctor or the Poison Control Center immediately. Overdose symptoms can include drowsiness, confusion, and seizures.
  • How long should I take Stogut 20 mg Tablet?: The length of treatment will depend on the specific condition being treated.
  • Is there anything else I should know about Stogut 20 mg Tablet?: It can cause dry mouth and constipation. Long-term use can lead to weak bones and a deficiency of minerals such as magnesium.

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