Mypril 2.5 mg (Tablet)

Unit Price: ৳ 5.00 (4 x 10: ৳ 200.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Ramipril
Company Eskayef pharmaceuticals ltd
Also available as

Indications

  • Hypertension
  • Congestive heart failure
  • Acute myocardial infarction treatment
  • Nephropathy treatment
  • Cardiovascular risk reduction

Pharmacology

  • Angiotensin converting enzyme inhibition
  • Vasopressor activity reduction
  • Aldosterone secretion decrease
  • Antihypertensive activity
  • Long-acting formulation

Dosage

  • Initial dose adjustment
  • Hypertension management dosage
  • Congestive heart failure after myocardial infarction dosage
  • Prevention of major cardiovascular events dosage
  • Renal impairment dosage

Administration

  • Oral administration
  • Swallow with liquid
  • Not to be chewed or crushed
  • Absorption not significantly affected by food

Interaction

  • Concomitant use with diuretics
  • Concomitant therapy with lithium
  • Impact of reduction in BP on ability to drive
  • NSAIDs impact on antihypertensive effect
  • Alcohol exacerbation of BP reduction

Contraindications

  • Hypersensitivity
  • History of angioedema
  • Concomitant sacubitril/valsartan therapy
  • Haemodynamically relevant renal artery stenosis
  • Hypotensive or haemodynamically unstable states
  • Concomitant use with certain medications
  • Pregnancy
  • Extracorporeal treatments

Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Hypotension
  • Cough
  • Nausea
  • Rash
  • Urticaria
  • Oliguria
  • Angioneurotic oedema
  • Anaphylactic reactions
  • Hyperkalaemia

Pregnancy & Lactation

  • Pregnancy exclusion before treatment
  • Avoidance of pregnancy during ACE inhibitor treatment
  • Discontinuation of ACE inhibitor during pregnancy
  • Breastfeeding recommendation

Precautions & Warnings

  • Caution in impaired renal function
  • Caution in hyperkalaemia
  • Caution in hypotension
  • Caution in impaired hepatic function

Use in Special Populations

  • Elderly dose considerations
  • Hepatic impairment treatment initiation
  • Renal impairment dose adjustment
  • Diuretic pretreatment considerations

Overdose Effects

  • Excessive peripheral vasodilatation
  • Hypotension
  • Bradycardia
  • Electrolyte disturbances
  • Renal failure

Therapeutic Class

  • Angiotensin-converting enzyme (ACE) inhibitors

Storage Conditions

  • Storage temperature and light protection
  • Expiry date adherence
  • Dispensing only on prescription

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