Mypril 5 mg (Tablet)

Unit Price: ৳ 8.00 (4 x 10: ৳ 320.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Ramipril
Company Eskayef pharmaceuticals ltd
Also available as

Indications

  • Hypertension
  • Congestive heart failure
  • Myocardial infarction treatment
  • Glomerular nephropathy treatment
  • Cardiovascular risk reduction

Pharmacology

  • Angiotensin converting enzyme (ACE) inhibitor
  • Decreased plasma angiotensin II
  • Vasopressor activity reduction
  • Aldosterone secretion decrease
  • Long-acting and well-tolerated

Dosage

  • Initial dose adjustment
  • Maintenance dosage
  • Renal impairment dosage adjustment
  • Dosage adjustment for heart failure
  • Dosage adjustment for prevention of major cardiovascular events

Administration

  • Swallowing with liquid
  • Not to be chewed or crushed
  • Absorption not affected by food
  • Can be taken before, during, or after a meal

Interaction

  • Concomitant diuretic administration
  • Concomitant therapy with lithium
  • Alcohol interaction
  • NSAIDs interaction

Contraindications

  • Hypersensitivity
  • History of angioedema
  • Concomitant sacubitril/valsartan therapy
  • Renal artery stenosis
  • Hypotensive or haemodynamically unstable states
  • Concomitant aliskiren-containing medicines

Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Symptomatic hypotension
  • Cough
  • Nausea
  • Vomiting
  • Diarrhoea
  • Rash
  • Urticaria
  • Oliguria
  • Anxiety
  • Amnesia
  • Angioneurotic oedema
  • Anaphylactic reactions
  • Hyperkalaemia

Pregnancy & Lactation

  • Not to be taken during pregnancy
  • Pregnancy exclusion before treatment
  • Consider alternative treatment during pregnancy
  • Not recommended during breastfeeding

Precautions & Warnings

  • Caution in impaired renal function
  • Caution in hyperkalaemia
  • Caution in hypotension
  • Caution in impaired hepatic function

Use in Special Populations

  • Reduced initial dose for Elderly
  • Treatment initiation with hepatic impairment under close supervision
  • Renal impairment considerations
  • Discontinuation of diuretic for patients pretreated with a diuretic

Overdose Effects

  • Excessive peripheral vasodilatation
  • Marked hypotension
  • Electrolyte disturbances
  • Renal failure

Therapeutic Class

Angiotensin-converting enzyme (ACE) inhibitors

Storage Conditions

  • Store at 30° or below
  • Protect from light
  • Keep out of the reach of children
  • Do not use later than the date of expiry

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