Zenilac 3.35 gm/5 ml (Oral Solution)

100 ml bottle: ৳ 120.00

Medicine Details

Category Details
Generic Lactulose
Company Zenith pharmaceuticals ltd

Title

  • Zenilac 3.35 gm/5 ml Oral Solution

Categories

  • Medicine
  • Healthcare
  • Laxative

Description

  • Zenilac is a hyperosmolar laxative
  • Used for constipation
  • Non-absorbable disaccharide
  • Draws water into the bowel
  • Causes distention through fluid accumulation
  • Promotes soft stool and accelerates bowel motion

Indications

  • Effective treatment for constipation
  • Treatment for chronic constipation
  • Diet rich in fiber and liquids as initial treatment
  • Treatment of intestinal flora disturbances
  • Reduction of blood ammonia levels

Pharmacology

  • Synthetic disaccharide
  • Metabolized in the colon by saccharolytic bacteria
  • Produces low molecular weight organic acids
  • Lowers the pH of the colon contents
  • Promotes retention of water by osmotic effect
  • Increases peristaltic activity
  • Minimally absorbed

Dosage and administration

  • Adult dosage of 3-6 tea-spoons daily for constipation
  • Children dosage of 3 tea-spoons daily for constipation
  • Infants and toddlers dosage of 1-2 tea-spoons daily for constipation
  • Adult dosage of 1-2 tea-spoons daily for damaged intestinal flora
  • Children dosage of 1 tea-spoon daily for damaged intestinal flora
  • Maximum dosage of 18-30 tea-spoons daily for reducing blood ammonia levels in hepatopathy
  • Hourly doses of 6-9 tea-spoons for inducing rapid laxation in portal systemic encephalopathy

Interaction

  • No significant drug interactions
  • Intensified glycosidic effect of cardiac glycosides by potassium deficiency in abuse

Contraindications

  • Hypersensitivity to galactose and lactose
  • Galactose-free diet
  • Gastro-cardial symptom complex
  • Suspected intestinal obstruction

Side effects

  • Flatulence
  • Cramp
  • Abdominal discomfort
  • Rapidly eliminated by reducing the dose
  • Overdose can result in diarrhea
  • Loss of electrolytes, primarily potassium

Pregnancy and lactation

  • US FDA Pregnancy Category B
  • No adverse effects reported
  • Decisions regarding use during pregnancy and lactation must be made by a registered physician

Precautions and warnings

  • Administered with care to patients intolerant to Zenilac
  • Higher dose in (pre)coma hepaticum may need to be considered for diabetics

Overdose effects

  • No reports of accidental overdosage
  • Expected symptoms of acute overdosage: diarrhea and abdominal cramps

Therapeutic class

  • Osmotic purgatives

Storage conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical structure

  • Molecular formula: C12H22O11
  • Chemical structure image available

Commonly asked questions

  • Use for treating constipation and reducing blood ammonia in liver disease
  • Frequency of use for constipation and liver disease
  • Time taken to see benefits of treatment
  • Usage for constipation symptoms
  • Confirmation of Zenilac as a laxative
  • Common side effects and their causes
  • Duration of use and patients to avoid
  • Consequences of taking more than the recommended dose

Additional info

  • Available as 3.35 gm/5 ml oral solution
  • No reports of significant drug interactions
  • Administered in various dosages for different indications
  • Suitable for use during pregnancy and lactation

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