Rantid 150 mg (Tablet)

Unit Price: ৳ 2.00

Medicine Details

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Prevention of ulcer associated with non-steroidal anti-inflammatory agent
  • Post operative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
  • Recurrent haemorrhage in patients with bleeding peptic ulcer
  • Before general anesthesia in patient considered to be at risk of acid aspiration
  • Particularly obstetric patients

Pharmacology

Competitively blocks histamine at H2-receptors of the gastric parietal cells which inhibits gastric acid secretion

Dosage & Administration

  • Usual dosage is 150 mg twice daily for 4 to 8 weeks
  • 150 mg at night for preventing recurrences
  • Children dosage: 2-4 mg/kg twice daily, maximum 300 mg daily

Interaction

May alter absorption of pH-dependent drugs and reduce bioavailability with antacids

Contraindications

Patients hypersensitive to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Ranitidine crosses the placenta
  • Used during pregnancy if considered essential
  • Excreted in human breast milk
  • Caution should be exercised when administered to a nursing mother

Precautions & Warnings

Given in reduced dosage to patients with impaired renal and hepatic function

Use in Special Populations

Similar ulcer healing rates in elderly patients

Overdose Effects

No particular problems expected following overdosage

Therapeutic Class

H2 receptor antagonist

Reconstitution

Multiple dilution and preparation options for intravenous administration

Storage Conditions

Store in a cool and dry place, protect from light

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