Phosphoprep (2.711 gm+1.2 gm)/5 ml (Oral Solution)

Indications

• Treats relief of occasional constipation
• Used for bowel cleansing regimen in preparing the patient for surgery
• Prepares the colon for X-Ray or endoscopic examination

Pharmacology

• Sodium phosphate management of hypophosphataemia
• Acts as a mild osmotic laxative when given orally as dilute solutions
• Phosphate enemas or concentrated oral solutions for bowel cleansing before surgery or endoscopy procedures

Dosage & Administration

• Recommended dosage for adults and children 5 years of age & over
• Dosage for bowel preparation in adults and children
• Dosage for occasional constipation in adults and children

Interaction

• Use with caution in patients taking specific medications affecting electrolyte levels
• Concurrent administration of polyethylene glycol bowel cleansing preparations and this solution may be dangerous and is not recommended

Contraindications

• Congestive heart failure
• Renal failure or clinically significant impaired renal function
• Bowel/GI obstructions
• Active inflammatory bowel disease

Side Effects

• Gastrointestinal side effects such as bloating, nausea, abdominal pain, and vomiting
• Nervous system side effects like dizziness, headache, and seizures
• Renal side effects including renal impairment, increased BUN, and acute renal failure
• Hypersensitivity reactions including anaphylaxis, rash, and bronchospasm

Pregnancy & Lactation

• Use not recommended in pregnant women unless the probable clinical benefit outweighs the possible risk
• Use not recommended in nursing mothers unless the probable clinical benefit outweighs the possible risk

Precautions & Warnings

• Use with extreme caution in the elderly, frail or debilitated
• Additional fluids by mouth for patients on a low salt diet
• Monitoring of electrolytes and intravenous fluids for patients undergoing major bowel procedures
• Caution advised in patients taking diuretics and medicines known to prolong the QT interval
• Advised not to use when nausea, vomiting, or abdominal pain are present

Use in Special Populations

• Not to be taken by children under 5 years of age
• Adjustment of insulin or oral anti-diabetic medication may be necessary for diabetic patients

Therapeutic Class

• Enema & bowel cleansing solution

Storage Conditions

• Store in a cool and dry place
• Protected from light
• Keep out of children's reach

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