Ethidin 150 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Ethical drugs limited |
Title
- Ethidin
- Ranitidine Tablet
- Ranitidine Syrup
Categories
- Medicine
- Gastrointestinal Treatment
Description
Ethidin (Ranitidine) is indicated for the treatment of active duodenal ulcer, benign gastric ulcer, ulcers associated with non-steroidal anti-inflammatory agents, postoperative stress ulcer, Zollinger-Ellison Syndrome, GERD, and gastrointestinal hemorrhage. It competitively blocks histamine at H2-receptors, inhibiting gastric acid secretion. The usual dosage is 150mg twice daily for duodenal and gastric ulcers, and 150mg 3 times daily for Zollinger-Ellison syndrome. It interacts with propantheline bromide, coumarin anticoagulants, theophylline, diazepam, propranolol, and pH-dependent drugs. It is contraindicated in patients hypersensitive to Ranitidine and should be used with caution in pregnant and lactating women, as well as in patients with impaired renal and hepatic function. It belongs to the therapeutic class of H2 receptor antagonist and should be stored in a cool and dry place, protected from light.
Size
Tablet: 150mg, Syrup: 15mg/1ml
Color Options
White (Tablet), Clear (Syrup)
Dosage & Administration
- 150 mg twice daily for duodenal and gastric ulcer
- 150 mg twice daily for reflux esophagitis
- 150 mg 3 times daily for Zollinger-Ellison syndrome
- 150 mg twice daily for episodic dyspepsia
- 150 mg at night for maintenance
- 2-4 mg/kg twice daily for children with peptic ulcer
- Slow IV injection, IV infusion for other conditions
- Doses for pediatric use
- Doses for elderly patients
Mode of Action
Competitively blocks histamine at H2-receptors, inhibiting gastric acid secretion
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of coumarin anticoagulants, theophylline, diazepam, and propranolol
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- Caution in nursing mothers
Precautions & Warnings
Should be given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
Similar ulcer healing rates in elderly patients, no difference in adverse effects
Overdose Effects
Specific in action, symptomatic and supportive therapy may be given if required, may be removed from plasma by haemodialysis
Therapeutic Class
H2 receptor antagonist
Reconstitution
Dilution instructions for slow IV injection, intermittent slow IV infusion, continuous IV infusion, and for Zollinger-Ellison syndrome
Storage Conditions
Cool and dry place, protected from light