Ultradin 75 mg/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Title

  • Ultradin Ranitidine Tablet & Syrup

Categories

  • Medicine
  • Gastrointestinal Drugs
  • H2-Receptor Antagonist

Description

  • Ranitidine competitively blocks histamine at H2-receptors of the gastric parietal cells which inhibits gastric acid secretion.
  • Ranitidine is indicated in the treatment of active duodenal ulcer, benign gastric ulcer, treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent, postoperative stress ulcer, Zollinger-Ellison Syndrome, gastroesophageal reflux disease (GERD)

Color Options

  • White

Dosage & Administration

  • 150 mg twice daily taken in the morning and evening or 300 mg as a single daily dose at night for 4 to 8 weeks for duodenal and gastric ulcer
  • 150 mg twice daily or 300 mg at bedtime for up to 8 weeks for reflux esophagitis
  • 150 mg 3 times daily and increased if necessary up to 6 g daily in divided doses for Zollinger Ellison syndrome
  • 150 mg twice daily or 300 mg at bedtime for up to 6 weeks for episodic dyspepsia
  • 150 mg at night for preventing recurrences for maintenance
  • 2-4 mg/kg twice daily, maximum 300 mg daily for children with peptic ulcer
  • Ranitidine injection may be given in a variety of methods for different indications

Interaction

  • Delayed absorption and increased peak serum concentration with propantheline bromide
  • Minimally inhibits hepatic metabolism of coumarin anticoagulants, theophylline, diazepam and propranolol
  • May alter absorption of pH-dependent drugs (e.g. ketoconazole, midazolam, glipizide)
  • May reduce bioavailability with antacids

Contraindications

  • Patients hypersensitive to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Ranitidine crosses the placenta
  • Ranitidine is excreted in human breast milk

Precautions & Warnings

  • Ultradin should be given in reduced dosage to patients with impaired renal and hepatic function

Use in Special Populations

  • Ulcer healing rates have been found similar in elderly patients
  • No difference in the incidence of adverse effects in elderly patients

Overdose Effects

  • Specific action with no particular problems expected following overdosage
  • Symptomatic and supportive therapy should be given as appropriate
  • If required, the drug may be removed from the plasma by hemodialysis

Therapeutic Class

  • H2 receptor antagonist

Reconstitution

  • Ultradin 50 mg diluted to a concentration ≤2.5 mg/mL with appropriate solutions for IV administration

Storage Conditions

  • Store in a cool and dry place
  • Protect from light

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