Ortac 50 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 6.04 (2 x 5: ৳ 60.40)

Medicine Details

Treatment of active duodenal ulcer
Benign gastric ulcer
Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
Post operative stress ulcer
Zollinger-Ellison Syndrome
Gastroesophageal reflux disease (GERD)
Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
Recurrent haemorrhage in patients with bleeding peptic ulcer
Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients

Competitively blocks histamine at H2-receptors
Inhibits gastric acid secretion
Does not affect pepsin secretion
Does not affect pentagastrin-stimulated intrinsic factor secretion or serum gastrin

Usual dosage of 150 mg twice daily for duodenal and gastric ulcer
300 mg as a single daily dose at night for 4 to 8 weeks for duodenal and gastric ulcer
150 mg twice daily for reflux oesophagitis
300 mg at bed time for up to 8 weeks for reflux oesophagitis
150 mg 3 times daily for Zollinger Ellison syndrome
150 mg twice daily for episodic dyspepsia
300 mg at bed time for up to 6 weeks for episodic dyspepsia
150 mg at night for maintenance
2-4 mg/kg twice daily for children with peptic ulcer
Ranitidine injection may be given intravenously or intramuscularly

Delayed absorption and increased peak serum concentration with propantheline bromide
Minimally inhibits hepatic metabolism of coumarin anticoagulants, theophylline, diazepam, and propanolol
May alter absorption of pH-dependent drugs
May reduce bioavailability with antacids