Duran 150 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Does not affect serum gastrin
Dosage & Administration
- Usual dosage is 150 mg twice daily for duodenal and gastric ulcer
- Dosage may be 300 mg as a single daily dose for 4 to 8 weeks
- Dosage for reflux oesophagitis is 150 mg twice daily
- Dosage for Zollinger Ellison syndrome is 150 mg 3 times daily
- Dosage for episodic dyspepsia is 150 mg twice daily
- Maintenance dosage is 150 mg at night
- Dosage for children with peptic ulcer is 2-4 mg/kg twice daily
- Intravenous injection dosage may be repeated every six to eight hours
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Caution during lactation
Precautions & Warnings
- Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No difference in adverse effects in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy recommended
- Haemodialysis may be used if required
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Specific dilution instructions for slow IV injection
- Specific dilution instructions for intermittent slow IV infusion
- Specific dilution instructions for continuous IV infusion
- Dilution instructions for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light