Anti-R 150 mg (Tablet)
Unit Price: ৳ 2.02 (10 x 10: ৳ 202.00)
Strip Price: ৳ 20.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | United pharmaceuticals ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Does not affect serum gastrin
Dosage & Administration
- Usual dosage of 150 mg twice daily for duodenal and gastric ulcer
- Dosage of 300 mg as a single daily dose at night for 4 to 8 weeks
- Dosage of 150 mg twice daily for Reflux oesophagitis
- Dosage of 300 mg at bed time for up to 8 weeks for Reflux oesophagitis
- Dosage of 150 mg 3 times daily for Zollinger Ellison syndrome
- Dosage increased if necessary up to 6 g daily in divided doses for Zollinger Ellison syndrome
- Dosage of 150 mg twice daily for Episodic dyspepsia
- Dosage of 300 mg at bed time for up to 6 weeks for Episodic dyspepsia
- Dosage of 150 mg at night for Maintenance
- Dosage of 2-4 mg/kg twice daily for Child (peptic ulcer)
- Maximum dosage of 300 mg daily for Child (peptic ulcer)
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Caution advised during pregnancy
- Excreted in human breast milk
- Caution advised when administered to nursing mothers
Precautions & Warnings
- Reduced dosage for patients with impaired renal function
- Reduced dosage for patients with impaired hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No significant difference in adverse effects in elderly patients
Overdose Effects
- Specific in action, limited problems expected
- Symptomatic and supportive therapy recommended
- May consider haemodialysis if needed
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Slow IV injection of Anti-R 50 mg
- Dilution to specific concentrations for different scenarios
- Different dilution protocols for specific conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light