Rifcin 150 mg (Capsule)
Unit Price: ৳ 11.03 (40's pack: ৳ 441.20)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rifampicin |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- treatment of tuberculosis
- treatment of meningococcal carrier state
- susceptibility testing before therapy
- monitoring response to treatment
- emergence of resistance
- modifying drug regimen
Pharmacology
- suppression of RNA synthesis
- binding to DNA-dependent RNA polymerase
- blockage of RNA transcription
Dosage
- oral administration
- IV infusion
- recommended doses for adults and pediatric patients
- administration with or without a meal
- initial phase of shortcourse therapy
- continuation of treatment
- treatment duration adjustments based on patient condition
Administration
- empty stomach administration
- timing of administration in relation to meals
Interaction
- acceleration of metabolism
- reduction of drug effect
- interactions with CYP450 metabolised drugs
- concurrent use effects
- risk of hepatotoxicity
Contraindications
- hypersensitivity
- history of hepatocellular toxicity
- interactions with other antiviral drugs
Side Effects
- facial flushing
- flu-like syndrome
- GI adverse effects
- pseudomembranous colitis
- alterations in kidney function
- menstrual disturbances
- orange-red discolouration of body fluids
- thrombophlebitis
- eye irritation
- anaphylaxis
Pregnancy & Lactation
- potential post natal hemorrhages
- tumorigenicity
- decision-making for nursing mothers
Precautions & Warnings
- liver dysfunction
- jaundice
- liver function monitoring
- competition with bilirubin for excretory pathways
- enzyme-inducing properties
- porphyria exacerbation
Use in Special Populations
- special considerations for geriatric use
Overdose Effects
- nausea
- abdominal pain
- pruritus
- lethargy
- hepatic involvement
- edema
- hypotension
- arrhythmias
- seizures
Therapeutic Class
- belongs to class of Anti-Tubercular Antibiotics
Reconstitution
- preparation of IV infusion solution
- reconstitution instructions
- stability of reconstituted solution
- dilution guidelines
Storage Conditions
- temperature range for storage
- protection from excessive heat and light