Rislock 4 mg (Tablet)

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

  • Selective monoaminergic antagonist
  • High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
  • Binds to alpha1 adrenergic receptors
  • Binds with lower affinity to H1 histamine and alpha2 adrenergic receptors
  • Potent D2 antagonist

Dosage & Administration

  • Initial dose 2 mg in 1-2 divided doses on 1st day
  • Usual dose range 4-6 mg daily
  • For mania, initial dose 2 mg once daily
  • For schizophrenia, initial dose 1 mg BID

Interaction

  • May antagonize the effects of levodopa and dopamine agonists
  • Reduces plasma clearance of Rislock when administered with carbamazepine
  • May decrease the clearance of Rislock when administered with clozapine
  • May enhance the effects of certain antihypertensives

Contraindications

  • Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Urine incontinence
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neutropenia
  • Thrombocytopenia

Pregnancy & Lactation

  • Did not show direct reproductive toxicity in experimental animals
  • Indirect prolactin- and CNS-mediated effects observed
  • No teratogenicity effect noted
  • Safety not established for use during human pregnancy
  • Excreted in breast milk, therefore breastfeeding not recommended

Precautions & Warnings

  • Preexisting cardiovascular diseases
  • Tardive dyskinesia
  • Renal and hepatic impairment
  • Elderly epilepsy
  • Parkinson's disease
  • Pregnancy

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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