Adrin 1 mg/ml (Injection)
1 ml ampoule: ৳ 25.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Adrenaline |
| Company | Gaco pharmaceuticals ltd |
Title
- Adrin
Categories
- Medicine
- Cardiac Arrest Management
- Resuscitation Aid
- Anaphylaxis Treatment
Description
- Direct-acting sympathomimetic agent
- Acts on alpha and beta-adrenoceptors
- Increases efficacy of basic life support
- Positive cardiac inotrope
- Increases systolic blood pressure
- Causes tachycardia and hyperglycemia
- Rapid onset and short duration
- Metabolized in liver and tissues
- Excreted in urine as metabolites
- Approximately 50% bound to plasma proteins
Indications
- Management of cardiac arrest
- Cardiopulmonary resuscitation
- Management of anaphylactic reactions
- Treatment of life-threatening asthma
Pharmacology
- Acts on alpha and beta receptor sites
- Rapid rise in blood pressure
- Stimulation of cardiac muscle
- Vasoconstriction in skin, mucosa, and splanchnic areas
- Moderate rise in systolic pressure with slow intravenous injection
Dosage and Administration
- Intravenous injection for cardiac arrest
- Endotracheal administration
- Intracardiac and intraspinal administration
- Dosage for anaphylaxis and asthma
- Dilution guidelines for adult dose
- Dosage for children based on body weight
Interactions
- Excessive doses of digitalis or mercurial diuretics not recommended
- Potentiated effects with tricyclic antidepressants and certain antihistamines
Contraindications
- Hypertension
- Arteriosclerosis
- Coronary disease
- Hyperthyroidism
- Patients taking monoamine oxidase inhibitors
Side Effects
- Anxiety
- Restlessness
- Dizziness
- Headache
- Palpitations
- Tremors
- Weakness
- Coldness of extremities
Pregnancy and Lactation
- Pregnancy Category C
- Crosses placenta and excreted in breast milk
- Use only if benefits outweigh risks to fetus
- Not recommended during lactation
Precautions and Warnings
- Avoid use of discolored solutions
- Avoid mixing with specific substances
- Caution in elderly and patients with certain conditions
Overdose Effects
- Cardiac arrhythmia
- Severe hypertension
- Counteraction with alpha and beta-adrenergic blocking agents
- Need for resuscitation support
Therapeutic Class
- Anaphylaxis
- Mydriatic and Cycloplegic agents
- Other adrenoceptor stimulants
- Respiratory stimulants: analeptics
Storage Conditions
- Store below 25°C
- Protect from light
- Keep out of the reach of children