Roxarel 10 mg (Tablet)
Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivaroxaban |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of atherothrombotic events in adult patients after an Acute Coronary Syndrome (ACS)
- Reduction in the risk of stroke and systemic embolism in nonvalvular atrial fibrillation
- Treatment of deep vein thrombosis (DVT) & pulmonary embolism (PE)
- Prophylaxis of DVT in patients undergoing knee or hip replacement surgery
Pharmacology
Highly selective direct factor Xa inhibitor, interrupts the blood coagulation cascade, does not inhibit thrombin or affect platelets
Dosage & Administration
- Recommended doses for different conditions and patient types
- Options for co-administration with other drugs
- Directions for taking with or without food
Interaction
Contraindicated with specific P-gp and CYP3A4 inhibitors and inducers, increased risk of bleeding with certain co-administered drugs
Contraindications
Known hypersensitivity to Rivaroxaban or excipients, active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
- Pregnancy category C, inadequate studies in pregnant women, dosing not established
- Unknown excretion in human milk, safety and efficacy not established in breastfeeding women
Precautions & Warnings
- Increased risk of thrombotic events upon early discontinuation
- Risk of fatal bleeding in the presence of specific risk factors
- Monitoring for neurological impairment in case of neuraxial anesthesia
- Not recommended in certain conditions
Overdose Effects
May lead to hemorrhage, limited absorption at single doses >50 mg
Therapeutic Class
Oral Anti-coagulants
Storage Conditions
Cool and dry place below 30°C, protected from light, keep away from children