Roxarel 15 mg (Tablet)
Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
Category | Details |
---|---|
Generic | Rivaroxaban |
Company | Incepta pharmaceuticals ltd |
Also available as |
Title
- Roxarel 2.5 mg
- Roxarel 10-20 mg
Categories
- Oral Anti-coagulants
Description
- Highly selective direct factor Xa inhibitor
- Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade
- Does not inhibit thrombin
- Increases risk of bleeding
- Pregnancy category C drug
Color Options
Dosage & Administration
- Recommended dose of 2.5 mg twice daily
- Recommended dose of 10-20 mg for different conditions
- May be taken with or without food
Mode of Action
- Inhibition of factor Xa
- Interruption of blood coagulation cascade
Interaction
- Contraindicated with ketoconazole, ritonavir, clarithromycin, etc.
- Decreases efficacy when co-administered with rifampicin, phenytoin, carbamazepine
- Increased risk of bleeding with anti-platelet agents, heparin, NSAIDs
Contraindications
- Known hypersensitivity to Rivaroxaban
- Active pathological bleeding
Side Effects
- Increased chance of bleeding
- Spinal or epidural hematoma
- Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation
Pregnancy & Lactation
- Pregnancy category C
- Safety and efficacy not established in breastfeeding women
Precautions & Warnings
- Increases risk of fatal bleeding in presence of certain risk factors
- Monitoring for signs of neurological impairment during neuraxial anesthesia
- Not recommended in unstable pulmonary embolism or thrombolysis cases
Overdose Effects
- May lead to hemorrhage
- Specific antidote not available
- Use of activated charcoal for overdose
Therapeutic Class
- Oral Anti-coagulants
Storage Conditions
- Store in cool place below 30°C
- Protected from light