Rosetor 20 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Aci limited |
| Also available as |
Indications
- Reduction of total-C, LDL-C, ApoB, non HDL-C, and TG levels
- Increase in HDL-C
- Adjunct to diet for patients with primary hyperlipidemia
- Adjunct to diet for patients with mixed dyslipidemia
- Adjunct to diet for patients with hypertriglyceridemia
- Adjunct to diet for patients with primary dysbetalipoproteinemia
- Reduction of LDL-C, total-C, and ApoB in patients with HoFH
- Slowing the progression of atherosclerosis
- Pediatric use for reducing total-C, LDL-C, and ApoB
- Risk reduction of Myocardial Infarction (MI), stroke, and arterial revascularization
Pharmacology
- Selective and competitive inhibitor of HMG-CoA reductase
- Increases the number of hepatic LDL receptors
- Enhances uptake and catabolism of LDL
- Inhibits hepatic synthesis of VLDL
- Reduces the total number of VLDL and LDL particles
Dosage and Administration
- Usual dose range of 5-20 mg/day for pediatric patients
- Maximum recommended dose of 20 mg/day for pediatric patients
- 40 mg once daily for very high cholesterol and high risk of MI or stroke
- Recommended starting dose of 20 mg once daily for HoFH
- Consider initiation with 5 mg once daily for Asian patients
- Limit dose to 5 mg once daily with Cyclosporine
- Limit dose to 10 mg once daily with Lopinavir/Ritonavir or Atazanavir/Ritonavir
- Consider reduction in dosage when used in combination with certain lipid-lowering therapies
- For severe renal impairment, start with 5 mg once daily and not exceed 10 mg once daily
Interaction
- Increased exposure with Cyclosporine, Lopinavir/Ritonavir, Atazanavir/Ritonavir
- Prolongation of international normalized ratio (INR) with coumarin anticoagulants
- Enhanced risk of skeletal muscle effects with certain lipid-lowering therapies
Contraindications
- Known hypersensitivity to product components
- Liver disease
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy and Lactation
- Administered to women of childbearing age only when highly unlikely to conceive
- Discontinue immediately if patient becomes pregnant
- Unknown excretion in human milk
Precautions and Warnings
- Prescribed with caution in patients with predisposing factors for myopathy
- Discontinue therapy in case of markedly elevated creatinine kinase levels
- Recommendation for liver enzyme tests
Overdose Effects
- No specific treatment
- Symptomatic treatment
- Supportive measures
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
Commonly Asked Questions
- Uses against Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia, and Stroke
- Side effects include Muscle pain, Weakness, Headache, and Abdominal pain
- Duration of treatment should be as per doctor's instructions
- Weight gain is a very rare side effect
- Tiredness and fatigue is a common side effect
- Avoid alcohol during the course of treatment
- Rosetor treats high cholesterol by lowering 'bad' cholesterol (LDL) and triglycerides
- Monitor liver function before and during treatment
- Do not take if pregnant, planning pregnancy, or breastfeeding