Bestcol 10 mg (Tablet)
Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Biopharma limited |
| Also available as |
Indications
- Primary hyperlipidemia and mixed dyslipidemia
- Hypertriglyceredemia
- Dysbetalipoproteinemia
- Homozygous familial hypercholesterolemia (HoFH)
- Slowing the progression of atherosclerosis
- Risk reduction of Myocardial Infarction (MI)
Pharmacology
- Selective and competitive inhibitor of HMG-CoA reductase
- Enhances uptake and catabolism of LDL
- Inhibits hepatic synthesis of VLDL
Dosage and administration
- Usual dose range of 5-20 mg/day
- Maximum recommended dose of 20 mg/day
- Recommended starting dose of 20 mg once daily for homozygous familial hypercholesterolemia
- Initiation with 5 mg once daily for Asian patients
- Dosage adjustment with concomitant medications
- Dosage limitation in severe renal impairment
Interaction
- Cyclosporine increases exposure
- Gemfibrosil combination to be avoided
- Increased exposure with Lopinavir/Ritonavir or Atazanavir/Ritonavir
- Prolongs international normalized ratio (INR) with coumarin anticoagulants
- Enhanced risk of skeletal muscle effects with concomitant lipid-lowering therapies
Contraindications
- Known hypersensitivity to product components
- Liver disease
- Pregnant women and women who may become pregnant
- Nursing mothers
Side effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy and lactation
- Administered to women of childbearing age only when highly unlikely to conceive
- Discontinue immediately if patient becomes pregnant
- Not known whether excreted in human milk
Precautions and warnings
- Prescribed with caution in patients with predisposing factors for myopathy
- Discontinue if markedly elevated creatinine kinase levels occur
- Temporary withholding in acute, serious conditions
- Liver enzyme tests to be performed periodically
Overdose effects
- No specific treatment
- Symptomatic treatment
- Hemodialysis does not significantly enhance clearance
Therapeutic class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical structure
- Molecular Formula: C22H28FN3O6S
Commonly asked questions
- What is Bestcol 10 mg Tablet?
- What are the uses of Bestcol 10 mg Tablet?
- What are the side effects of Bestcol 10 mg Tablet?
- For how long should I take Bestcol 10 mg Tablet?
- Does Bestcol 10 mg Tablet cause weight gain?
- Does Bestcol 10 mg Tablet make you tired?
- Should Bestcol 10 mg Tablet be taken at night?
- What foods should be avoided when taking Bestcol 10 mg Tablet?
- How do I know whether Bestcol 10 mg Tablet is beneficial for me or not?
- Can Bestcol 10 mg Tablet cause memory loss?
- Is it true that Bestcol 10 mg Tablet can cause diabetes?
- Can I take alcohol with Bestcol 10 mg Tablet?
- Can Bestcol 10 mg Tablet cause muscle problems or muscle injury?
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