Rocovas 5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Product Title

  • Rocovas 5 mg Tablet

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Indications

  • Adjunct to diet for reducing elevated total-C, LDL-C, ApoB, non HDL-C and TG levels
  • Treatment of hypertriglyceredemia
  • Treatment for primary dysbetalipoproteinemia (Type III hyperlipoproteinemia)
  • Reducing LDL-C, total-C, and ApoB for patients with homozygous familial hypercholesterolemia (HoFH)
  • Slowing the progression of atherosclerosis
  • Risk reduction of Myocardial Infarction (MI), stroke and arterial revascularization procedures
  • Reducing elevated total-C, LDL-C and ApoB in pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH)

Pharmacology

  • Selective and competitive inhibitor of HMG-CoA reductase
  • Increases hepatic LDL receptors on the cell surface to enhance uptake and catabolism of LDL
  • Inhibits hepatic synthesis of VLDL, reducing the total number of VLDL and LDL particles

Dosage & Administration

  • Usual dose range of 5-20 mg/day for pediatric patients 10 to 17 years of age
  • 40 mg once daily for very high cholesterol and high risk of MI or stroke
  • Recommended starting dose of 20 mg once daily for homozygous familial hypercholesterolemia
  • Initiation with 5 mg once daily for Asian patients
  • Dose limitations with concomitant use of Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir
  • Consideration of dose reduction with concomitant use of Niacin or Fenofibrate
  • Dosing considerations for patients with severe renal impairment

Interaction

  • Increased exposure with concomitant use of Cyclosporine, Gemfibrosil, Lopinavir/Ritonavir or Atazanavir/Ritonavir
  • Prolonged international normalized ratio (INR) with concomitant use of Coumarin anticoagulants
  • Enhanced risk of skeletal muscle effects with concomitant lipid-lowering therapies

Contraindications

  • Known hypersensitivity to product components
  • Liver disease
  • Pregnant women and women who may become pregnant
  • Nursing mothers

Side Effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy & Lactation

  • Administered to women of childbearing age only when conception is highly unlikely
  • Discontinuation of therapy if patient becomes pregnant
  • Potential excretion in human milk

Precautions & Warnings

  • Prescribed with caution in patients with predisposing factors for myopathy
  • Increased risk of myopathy with concurrent administration of some other lipid-lowering therapies, Gemfibrozil, Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir
  • Discontinuation of therapy in case of markedly elevated creatinine kinase levels or myopathy diagnosis
  • Temporary withholding of therapy in patients with acute, serious conditions suggestive of myopathy or predisposing to the development of renal failure
  • Recommendation for liver enzyme tests before and following initiation of therapy and any dose elevation

Overdose Effects

  • No specific treatment
  • Symptomatic treatment and supportive measures

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C22H28FN3O6S

Common Questions

  • Uses of Rocovas 5 mg Tablet include Hyperlipidemia, Hypertriglyceridemia...
  • Side effects include Muscle pain, Weakness, Headache...
  • Duration of Rocovas 5 mg Tablet to be determined by doctor...
  • Rocovas 5 mg Tablet does not cause weight gain...
  • Tiredness and fatigue are common side effects of Rocovas 5 mg Tablet...
  • Rocovas 5 mg Tablet need not be taken at night...
  • Avoid high calorie and junk foods during Rocovas 5 mg Tablet treatment...
  • Improvement in medical condition indicates benefit of Rocovas 5 mg Tablet...
  • Rocovas 5 mg Tablet may cause muscle problems or injury...
  • Quick Tips for using Rocovas 5 mg Tablet

Storage Image

  • URL to the chemical structure image

Dosing Instructions

  • Specific dosing instructions for different patient populations

Drug Interaction

  • Detailed information on potential drug interactions

Adverse Reactions

  • Comprehensive list of potential side effects

Pregnancy Warnings

  • Guidance on pregnancy and lactation usage

Advisory Information

  • Important cautions and warnings for usage

Overdose Management

  • Information on managing an overdose

FAQs

  • Common questions and answers about the product

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