Rolip 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Renata limited |
| Also available as |
Title
Rolip 5 mg Tablet
Categories
- Anti-cholesterol
- Statins
Description
Rolip is indicated for patients with primary hyperlipidemia and mixed dyslipidemia as an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non HDL-C and TG levels and to increase HDL-C. It is also used for patients with hypertriglyceredemia as an adjunct to diet, patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an adjunct to diet, patients with homozygous familial hypercholesterolemia to reduce LDL-C, total-C, and ApoB, slowing the progression of atherosclerosis as part of a treatment strategy to lower total-C and LDL-C, pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia to reduce elevated total-C, LDL-C and ApoB after failing an adequate trial of diet therapy, and risk reduction of Myocardial Infarction (MI), stroke, and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors.
Dimensions
- Estimated tablet size
Color Options
Functions
- Lowers total-C, LDL-C, ApoB, non HDL-C, and TG levels
- Increases HDL-C
- Slows the progression of atherosclerosis
- Reduces the risk of Myocardial Infarction (MI), stroke, and arterial revascularization procedures
Materials
- Active Ingredient: Rosuvastatin calcium
Technical Specifications
- Molecular Formula: C22H28FN3O6S
Design Elements
Usability Features
- Indicated for pediatric use (10 to 17 years of age)
Dosage Range
- 5-20 mg/day for Heterozygous Familial Hypercholesterolemia in Pediatric Patients (10 to 17 years of age)
- 40 mg once daily for very high cholesterol and high risk of MI or stroke
- 20 mg once daily for Homozygous Familial Hypercholesterolemia
- Initiation with 5 mg once daily for Asian patients
- Limited dosage with certain drug combinations and in severe renal impairment
Interactions
- Cyclosporine increases Rosuvastatin exposure and limits dosage
- Gemfibrosil should be avoided or limits dosage
- Lopinavir/Ritonavir or atazanavir/ritonavir increases Rosuvastatin exposure and limits dosage
- Coumarin anticoagulants prolong international normalized ratio (INR)
- Enhanced risk of skeletal muscle effects with concomitant lipid-lowering therapies
Contraindications
- Known hypersensitivity to product components
- Liver disease, including unexplained persistent elevations in hepatic transaminase levels
- Pregnant women and women who may become pregnant
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
- Administered to women of childbearing age only when highly unlikely to conceive
- Discontinued immediately if patient becomes pregnant
- Unknown excretion in human milk
Precautions & Warnings
- Prescribed with caution in patients with predisposing factors for myopathy
- Therapy should be discontinued or temporarily withheld in certain conditions
- Recommended liver enzyme tests before and during therapy
Overdose Effects
- No specific treatment in the event of overdose
- Symptomatic and supportive measures instituted as required
- Hemodialysis does not significantly enhance clearance of Rolip
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C22H28FN3O6S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-970-rosuvastatin-calcium-chemical-structure-UjXgzBvpDHiLnIP3gZua.svg
Commonly Asked Questions
- What is Rolip 5 mg Tablet?
- What are the uses of Rolip 5 mg Tablet?
- What are the side effects of Rolip 5 mg Tablet?
- For how long should I take Rolip 5 mg Tablet?
- Does Rolip 5 mg Tablet cause weight gain?
- Does Rolip 5 mg Tablet make you tired?
- Should Rolip 5 mg Tablet be taken at night?
- What foods should be avoided when taking Rolip 5 mg Tablet?
- How do I know whether Rolip 5 mg Tablet is beneficial for me or not?
- Can Rolip 5 mg Tablet cause memory loss?
- Is it true that Rolip 5 mg Tablet can cause diabetes?
- Can I take alcohol with Rolip 5 mg Tablet?
- Can Rolip 5 mg Tablet cause muscle problems or muscle injury?
- Quick Tips
Indications
- Primary hyperlipidemia and mixed dyslipidemia
- Hypertriglyceredemia
- Primary dysbetalipoproteinemia (Type III hyperlipoproteinemia)
- Homozygous familial hypercholesterolemia (HoFH)
- Slowing the progression of atherosclerosis
- Pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH)
- Risk reduction of Myocardial Infarction (MI), stroke, and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors
Pharmacology
Selective and competitive inhibitor of HMG-CoA reductase; increases hepatic LDL receptors; inhibits hepatic synthesis of VLDL
Interaction
- Cyclosporine: Increases Rolip exposure and limits dosage
- Gemfibrosil: Avoid or limit dosage
- Lopinavir/Ritonavir or atazanavir/ritonavir: Increases Rolip exposure and limits dosage
- Coumarin anticoagulants: Prolongs international normalized ratio (INR)
- Concomitant lipid-lowering therapies: Enhanced risk of skeletal muscle effects