Corestin 20 mg (Tablet)

Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00

Medicine Details

Category Details
Generic Rosuvastatin calcium
Company Unimed unihealth pharmaceuticals ltd
Also available as
Corestin 5 mg tablet Corestin 10 mg tablet

Title

  • Corestin 20 mg Tablet

Categories

  • Medicine
  • Health & Wellness
  • Pharmaceuticals

Description

  • Corestin is a medication indicated for the treatment of primary hyperlipidemia, mixed dyslipidemia, and other related conditions. It acts as an adjunct to diet to reduce elevated cholesterol levels and triglycerides while increasing HDL-C. The pharmacological action of Rosuvastatin involves inhibiting HMG-CoA reductase, thereby reducing cholesterol synthesis and enhancing LDL receptor expression. The dosage and administration vary for different patient populations and conditions, and caution should be exercised in patients with predisposing factors for myopathy. Corestin exhibits drug interactions with Cyclosporine, Gemfibrosil, Lopinavir/Ritonavir, Atazanavir/Ritonavir, and concomitant lipid-lowering therapies, and is contraindicated in individuals with known hypersensitivity to its components, liver disease, pregnant or nursing women. Commonly asked questions about Corestin include queries related to its uses, side effects, duration of use, and precautions. It belongs to the therapeutic class of Other Anti-anginal & Anti-ischaemic drugs, Statins, and should be stored below 30°C, protected from light & moisture, and out of the reach of children.

Dimensions

  • 20 mg Tablet

Color options

Functions

  • Lowers cholesterol levels
  • Reduces triglycerides
  • Increases HDL-C
  • Inhibits HMG-CoA reductase
  • Enhances LDL receptor expression

Materials

Technical specifications

  • Molecular Formula: C22H28FN3O6S
  • Chemical Structure: Image URL of Rosuvastatin Calcium Chemical Structure

Design elements

Usability features

  • Dosage Range: 5-20 mg/day
  • Maximum Recommended Dose: 20 mg/day
  • Dosage Adjustment Intervals: 4 weeks or more
  • Dosage in Asian Patients: Initiation with 5 mg once daily
  • Use with Cyclosporine, Lopinavir/Ritonavir or Atazanavir/Ritonavir: Limit dosage accordingly
  • Concomitant Lipid-Lowering Therapy: Consider reduction in Rosuvastatin dosage
  • Dosage in Patients with Severe Renal Impairment: Start at 5 mg once daily, not to exceed 10 mg once daily

Indications

  • Primary hyperlipidemia
  • Mixed dyslipidemia
  • Hypertriglyceredemia
  • Primary dysbetalipoproteinemia
  • Homozygous familial hypercholesterolemia (HoFH)
  • Slowing the progression of atherosclerosis
  • Pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH)
  • Risk reduction of Myocardial Infarction (MI), stroke and arterial revascularization procedures in patients without clinically evident CHD

Interaction

  • Cyclosporine
  • Gemfibrosil
  • Lopinavir/Ritonavir or atazanavir/ritonavir
  • Coumarin anticoagulants
  • Concomitant lipid-lowering therapies

Contraindications

  • Known hypersensitivity to product components
  • Liver disease
  • Pregnant women
  • Nursing mothers

Side effects

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea

Pregnancy and lactation

  • Administered to women of childbearing age only when unlikely to conceive
  • Immediate discontinuation if pregnant while taking the drug
  • Potential excretion in human milk

Precautions and warnings

  • Prescribed with caution in patients with predisposing factors for myopathy
  • Discontinuation if markedly elevated creatinine kinase levels or myopathy occur
  • Temporary withholding in patients with acute, serious conditions
  • Recommended liver enzyme tests before and at intervals following therapy initiation or dose elevation

Overdose effects

  • No specific treatment in the event of overdose
  • Symptomatic treatment and supportive measures

Therapeutic class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Other common questions

  • What is Corestin 20 mg Tablet?: HMG-CoA reductase inhibitor for lowering cholesterol and triglycerides.
  • What are the uses of Corestin 20 mg Tablet?: Useful against Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia, and Stroke.
  • What are the side effects of Corestin 20 mg Tablet?: Muscle pain, Weakness, Headache, and Abdominal pain.
  • For how long should I take Corestin 20 mg Tablet?: Until improvement observed; follow doctor’s instructions.
  • Does Corestin 20 mg Tablet cause weight gain?: Very rare; not typical.
  • Does Corestin 20 mg Tablet make you tired?: Tiredness and fatigue are common side effects; consult a doctor if persistent.
  • Should Corestin 20 mg Tablet be taken at night?: Not mandatory; follow doctor’s dosage instructions.
  • What foods should be avoided when taking Corestin 20 mg Tablet?: Avoid junk food and high-calorie foods.
  • How do I know whether Corestin 20 mg Tablet is beneficial for me or not?: Notice improvement; consult a doctor if adverse effects.
  • Can Corestin 20 mg Tablet cause memory loss?: Very unusual side effect; consult a doctor if experienced.
  • Is it true that Corestin 20 mg Tablet can cause diabetes?: Does not cause diabetes; monitor blood sugar levels if at risk.
  • Can I take alcohol with Corestin 20 mg Tablet?: Avoid alcohol during treatment.
  • Can Corestin 20 mg Tablet cause muscle problems or muscle injury?: Muscle pain is a common side effect; consult a doctor if discomfort persists.
  • Quick Tips: Treatment alongside regular exercise and low-fat diet; notify doctor for any adverse effects or medical conditions.

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