Rosterol 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | United pharmaceuticals ltd |
Title
Rosterol 10 mg Tablet
Categories
- Medicine
- Pharmaceuticals
- Health & Wellness
Description
Rosterol is a medication indicated for primary hyperlipidemia, mixed dyslipidemia, hypertriglyceredemia, dysbetalipoproteinemia, homozygous familial hypercholesterolemia, atherosclerosis, pediatric patients with heterozygous familial hypercholesterolemia, risk reduction of Myocardial Infarction (MI) and stroke, and as a part of a treatment strategy. It is a selective and competitive inhibitor of HMG-CoA reductase, and the dosage, administration, interactions, contraindications, side effects, pregnancy & lactation, precautions & warnings, overdose effects, therapeutic class, storage conditions, and chemical structure, among others.
DosageRange
5-20 mg/day
UsualDosage
5-20 mg/day
MaximumRecommendedDosage
20 mg/day
MaximumStudiedDosage
20 mg/day
PediatricDosage
10 to 17 years of age
RecommendedStartingDosage
20 mg once daily
DosageForAsianPatients
5 mg once daily
DosageWithCertainMedications
- Cyclosporine: limited to 5 mg once daily
- Lopinavir/Ritonavir or Atazanavir/Ritonavir: limited to 10 mg once daily
ConcomitantLipidLoweringTherapy
possible reduction in Rosterol dosage
DosageInPatientsWithSevereRenalImpairment
started at 5 mg once daily, not to exceed 10 mg once daily
DrugInteractions
- Cyclosporine
- Gemfibrosil
- Lopinavir/Ritonavir
- Atazanavir/Ritonavir
- Coumarin anticoagulants
- Concomitant lipid-lowering therapies
Contraindications
- Known hypersensitivity to product components
- Liver disease
- Pregnant women
- Nursing mothers
SideEffects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy&Lactation
- AdministrationToWomenOfChildbearingAge: highly unlikely to conceive
- Pregnancy: discontinue immediately if pregnant
- Lactation: unknown excretion in human milk
Precautions&Warnings
- PredisposingFactorsForMyopathy: age >65 years, inadequately treated hypothyroidism, renal impairment
- IncreaseRiskOfMyopathyWithConcurrentAdministrationOf:
- Fibrates or Niacin
- Gemfibrozil
- Cyclosporine
- Lopinavir/Ritonavir
- Atazanavir/Ritonavir
- RecommendationsForLiverEnzymeTests: before and at 12 weeks following the initiation of therapy and periodically (e.g., semiannually) thereafter
OverdoseEffects
no specific treatment, symptomatic and supportive measures
TherapeuticClass
Other Anti-anginal & Anti-ischaemic drugs, Statins
StorageConditions
below 30°C temperature, protected from light & moisture, keep out of the reach of children