Liconor 250 mg/5 ml (Oral Suspension)

50 ml bottle: ৳ 180.68

Medicine Details

Indications

  • Cholestasis (Jaundice)
  • Viral Hepatitis
  • Alcoholic Fatty Liver
  • Primary Billiary Cirrhosis (PBC)
  • Primary Sclerosing Cholangitis (PSC)
  • Dissolution of Gallstones
  • Non-Alcoholic Steato Hepatitis (NASH)

Description

Reduces cholesterol saturation of bile, promoting dissolution of gallstones and reducing cholesterol secretion into bile.

Pharmacology

  • Decreases secretion of cholesterol in bile
  • Reduces cholesterol absorption
  • Suppresses liver cholesterol synthesis
  • Promotes formation of liquid cholesterol crystal complexes
  • Protects cholangiocytes against cytotoxicity of hydrophobic bile acids
  • Stimulates hepatobilliary secretion

Dosage & Administration

  • Dissolution of Gall stones: 8-12 mg/kg/day
  • Primary Billiary Cirrhosis: 10-15 mg/kg/day
  • Acute Viral Hepatitis: 600 mg/day
  • Alcoholic Fatty Liver: 300 mg/day
  • Primary Sclerosing Cholangitis: 25-30 mg/kg/day

Interaction

Should not be used with oestrogenic hormones or bile-acid binding drugs

Contraindications

  • Non-functioning gall-bladder
  • Calcified and pigmented gallstones
  • Inflammatory bowel disease

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Gallstone opacilication
  • Pruritus

Pregnancy & Lactation

Pregnancy category B. No evidence of harm in pregnancy or breastfeeding documented.

Precautions & Warnings

Use cautiously in those with liver disease

Therapeutic Class

Anti-gallstones drugs: Bile Acids

Storage Conditions

Store below 25°C, protected from light and moisture, keep out of reach of children

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