Liconor 250 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 180.68
Medicine Details
Category | Details |
---|---|
Generic | Ursodeoxycholic acid |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Billiary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steato Hepatitis (NASH)
Description
Reduces cholesterol saturation of bile, promoting dissolution of gallstones and reducing cholesterol secretion into bile.
Pharmacology
- Decreases secretion of cholesterol in bile
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Promotes formation of liquid cholesterol crystal complexes
- Protects cholangiocytes against cytotoxicity of hydrophobic bile acids
- Stimulates hepatobilliary secretion
Dosage & Administration
- Dissolution of Gall stones: 8-12 mg/kg/day
- Primary Billiary Cirrhosis: 10-15 mg/kg/day
- Acute Viral Hepatitis: 600 mg/day
- Alcoholic Fatty Liver: 300 mg/day
- Primary Sclerosing Cholangitis: 25-30 mg/kg/day
Interaction
Should not be used with oestrogenic hormones or bile-acid binding drugs
Contraindications
- Non-functioning gall-bladder
- Calcified and pigmented gallstones
- Inflammatory bowel disease
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Gallstone opacilication
- Pruritus
Pregnancy & Lactation
Pregnancy category B. No evidence of harm in pregnancy or breastfeeding documented.
Precautions & Warnings
Use cautiously in those with liver disease
Therapeutic Class
Anti-gallstones drugs: Bile Acids
Storage Conditions
Store below 25°C, protected from light and moisture, keep out of reach of children