Rupa 5 mg/5 ml (Oral Solution)

60 ml bottle: ৳ 75.00

Medicine Details

Category Details
Generic Rupatadine fumarate
Company Aristopharma ltd
Also available as
Rupa 10 mg tablet

Indications

  • Seasonal Allergic Rhinitis
  • Perennial Allergic Rhinitis
  • Urticaria

Pharmacology

  • Long-acting non-sedative histamine H1-receptor antagonist
  • Platelet activating factor (PAF) antagonist
  • Bronchoconstriction prevention
  • Inhibition of mast cell degranulation and cytokine release

Dosage & Administration

  • Adults and Adolescents: 10 mg once a day
  • Children 2-11 years:
    • 1 teaspoonful (5 ml) for children weighing 25 kg or more
    • 1/2 teaspoonful (2.5 ml) for children weighing 10-25 kg

Interaction

  • Medicine:
    • Caution with ketoconazole or erythromycin
    • Caution with statins, CNS depressants, or alcohol
  • Food: Avoid simultaneous intake with grapefruit or grapefruit juice

Contraindications

  • Hypersensitivity to Rupatadine or excipients

Side Effects

  • Common:
    • Asthenia
    • Dizziness
    • Drowsiness
  • Uncommon:
    • Increased appetite
    • Arthralgia
    • Back pain
    • Impaired concentration
    • Constipation
    • Cough
    • Diarrhea
    • Dry throat
    • Epistaxis
    • Fever
    • Increased infection risk
    • Irritability
    • Malaise
    • Myalgia
    • Nasal dryness
    • Nausea
    • Oropharyngeal pain
    • Rash
    • Thirst
    • Vomiting
    • Increased weight
  • Rare:
    • Palpitations
    • Tachycardia

Pregnancy & Lactation

  • Avoid use during pregnancy unless benefits outweigh risks
  • Avoid use during lactation unless benefits justify potential risks

Precautions & Warnings

  • General: Caution with QT interval prolongation, hypokalemia, proarrhythmic conditions, and in elderly
  • Special Populations:
    • Use with caution in elderly (no dose adjustments required)
    • Not established for children under 12 years
    • Not recommended for patients with renal or hepatic insufficiency

Use in Special Populations

  • Elderly: Caution without dose adjustment
  • Children: Not established for patients under 12 years
  • Renal or Hepatic Insufficiency: Not recommended due to lack of clinical data

Overdose Effects

Common adverse reaction is somnolence

Therapeutic Class

Non-sedating antihistamines

Storage Conditions

Store below 30°C, protect from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C26H26ClN3
  • Chemical Structure: Image URL

Common Questions

  • What is Rupa 5 mg/5 ml Solution?: H1-receptors antagonist
  • What is it used for?: Treatment of seasonal & perennial allergic rhinitis and urticaria
  • Pregnancy warnings: Unsafe to use during pregnancy
  • Breast-feeding warnings: Unknown, consult doctor
  • Safety for driving: Data unavailable, consult doctor
  • Effect on kidney function: Caution in renal impairment
  • Effect on liver function: Data unavailable, consult doctor
  • Onset of action: Within 75 minutes after administration
  • Duration of effect: 8 to 10 hours
  • Quick Tips:
    • Relieves allergy symptoms
    • Less likely to cause sleepiness compared to other medications
    • Caution while driving or doing tasks requiring concentration
    • Avoid alcohol intake
    • Stop taking before allergy test

Related Brands