Rupana 10 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Symptomatic treatment of Seasonal Allergic Rhinitis
  • Symptomatic treatment of Perennial Allergic Rhinitis
  • Symptomatic treatment of Urticaria

Pharmacology

  • Long-acting non-sedative antagonist of histamine H1-receptors
  • Antagonist of platelet activating factor (PAF)
  • Inhibition of degranulation of mast cells
  • Inhibition of release of cytokines
  • Dual mode of action for better therapeutic effect

Dosage & Administration

  • Recommended dose for adults and adolescents is 10 mg once a day
  • Can be taken with or without food
  • Different dosage for children based on weight

Interaction

  • Increased systemic exposure with concomitant administration of ketoconazole or erythromycin
  • Caution required when administered with statins, CNS depressants, or alcohol
  • Grapefruit and grapefruit juice should not be taken simultaneously

Contraindications

  • Hypersensitivity to Rupatadine or any of the excipients

Side Effects

  • Common: Asthenia, dizziness, drowsiness
  • Uncommon: Appetite increased, arthralgia, back pain, diarrhea, dry throat, fever, rash, vomiting
  • Rare: Palpitations, tachycardia

Pregnancy & Lactation

  • Not recommended during pregnancy unless benefits outweigh risks
  • Not recommended during lactation unless benefits justify risks

Precautions & Warnings

  • Use with caution in patients with known prolongation of the QT interval
  • Use with caution in elderly patients
  • Not recommended for patients with impaired kidney or liver function

Use in Special Populations

  • Caution advised in elderly patients
  • Not established for patients under 12 years of age
  • Not recommended for patients with renal or hepatic insufficiency

Overdose Effects

  • Most common adverse reaction: somnolence
  • Symptomatic treatment and supportive measures required for very high doses

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C26H26ClN3
  • Chemical Structure available

Common Questions about Rupana 10 mg Tablet

  • H1-receptors antagonist
  • Used for treating seasonal & perennial allergic rhinitis and urticaria
  • Pregnancy warnings
  • Breast-feeding warnings
  • Safety for driving
  • Effect on kidney function
  • Effect on liver function
  • Onset of action within 75 minutes
  • Duration of effect: 8 to 10 hours
  • Quick tips for usage

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