Rupex 5 mg/5 ml (Oral Solution)

60 ml bottle: ৳ 75.00

Medicine Details

Category Details
Generic Rupatadine fumarate
Company Incepta pharmaceuticals ltd
Also available as

Indications

  • Symptomatic treatment of Seasonal Allergic Rhinitis
  • Symptomatic treatment of Perennial Allergic Rhinitis
  • Symptomatic treatment of Urticaria

Pharmacology

  • Long-acting non-sedative antagonist of histamine H1-receptors
  • Dual mode of action against histamine and platelet activating factor (PAF)
  • Inhibition of degranulation of mast cells
  • Inhibition of release of cytokines

Dosage & Administration

  • Recommended dose for adults and adolescents (over 12 years): 10 mg once a day
  • Recommended dose for children aged 2 to 11 years based on weight

Interaction

  • Increased systemic exposure when co-administered with ketoconazole or erythromycin
  • Caution required when co-administered with statins, CNS depressants, or alcohol
  • Grapefruit and Grapefruit juice should not be taken simultaneously

Contraindications

  • Hypersensitivity to Rupatadine or any of the excipients

Side Effects

  • Common: Asthenia, dizziness, drowsiness
  • Uncommon: Appetite increased, arthralgia, back pain, concentration impaired
  • Rare: Palpitations, tachycardia

Pregnancy & Lactation

  • Not recommended during pregnancy unless benefits outweigh risks
  • Not recommended during lactation unless benefits justify risks

Precautions & Warnings

  • Caution in patients with known prolongation of the QT interval
  • Caution in patients with uncorrected hypokalemia
  • Caution in elderly patients

Use in Special Populations

  • Caution in elderly patients
  • Safety and efficacy not established in patients less than 12 years of age
  • Not recommended in patients with renal or hepatic insufficiency

Overdose Effects

  • Most common adverse reaction: Somnolence
  • Symptomatic treatment and supportive measures required for accidental ingestion of very high doses

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C26H26ClN3
  • Chemical Structure Image URL: [URL]

Common Questions about Rupex 5 mg/5 ml Oral Solution

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