Paftrol 5 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rupatadine fumarate |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic treatment of Seasonal Allergic Rhinitis
- Symptomatic treatment of Perennial Allergic Rhinitis
- Symptomatic treatment of Urticaria
Pharmacology
- Long-acting non-sedative antagonist of histamine H1-receptors
- Antagonizes platelet activating factor (PAF)
- Inhibition of degranulation of mast cells
- Inhibition of release of cytokines
Dosage and administration
- Recommended adult dose: 10mg once a day
- Recommended children dose (25 kg or more): 5ml oral solution once daily
- Recommended children dose (10 kg to less than 25 kg): 2.5ml oral solution once daily
Interaction
- Concomitant administration with ketoconazole or erythromycin increases systemic exposure
- Caution with statins, CNS depressants, or alcohol
- Avoid simultaneous intake with grapefruit or grapefruit juice
Contraindications
- Hypersensitivity to Rupatadine or any excipients
Side effects
- Common: Asthenia, dizziness, drowsiness
- Uncommon: Increased appetite, arthralgia, back pain, impaired concentration
- Rare: Palpitations, tachycardia
Pregnancy and lactation
- Not recommended during pregnancy unless benefits outweigh risks
- Not recommended during lactation unless benefits justify risks
Precautions and warnings
- Caution in patients with known prolongation of the QT interval
- Caution in patients with uncorrected hypokalemia
- Caution in elderly patients (65 years and older)
Use in special populations
- Caution in elderly patients
- No established safety or efficacy in patients less than 12 years of age
- Not recommended in patients with renal or hepatic insufficiency
Overdose effects
- Most common adverse reaction: somnolence
- Symptomatic treatment and supportive measures in case of accidental ingestion of high doses
Therapeutic class
- Non-sedating antihistamines
Storage conditions
- Store below 30°C in a cool, dry place
- Protect from light and moisture
- Keep out of reach of children
Chemical structure
- Molecular Formula: C26H26ClN3
Common questions
- What is Paftrol 5 mg/5 ml Solution?
- What is Paftrol 5 mg/5 ml Solution used for?
- Are there any pregnancy warnings?
- Are there any breast-feeding warnings?
- Is it safe to drive while on Paftrol 5 mg/5 ml Solution?
- Does this affect kidney function?
- Does Paftrol 5 mg/5 ml Solution affect liver function?
- What is the onset of action of Paftrol 5 mg/5 ml Solution?
- How long is the duration of effect?
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