Sertlin 25 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Albion laboratories limited |
| Also available as |
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. Prolonged elimination half-life offers a benefit of once daily administration.
Dosage & Administration
- Adults:
- Starting Dose: 50 mg
- Therapeutic Range: 50-200 mg
- Pediatric Patients (ages 6-12 years old):
- Starting Dose: 25 mg
- Therapeutic Range: 50-200 mg
- Premenstrual dysphoric disorder (PMDD):
- Starting dosage for PMDD is 50 mg/day
- Sertraline may be administered either continuously (every day throughout the menstrual cycle) or intermittently (starting the daily dosage 14 days prior to the anticipated onset of menstruation and continuing through the onset of menses).
- Patients not responding to a 50 mg dosage may benefit from dosage increases at 50 mg increments per menstrual cycle up to 150 mg per day.
- Patients not responding to a 50 mg dosage may benefit from increasing the dosage up to a maximum of 100 mg per day during the next menstrual cycle
Interaction
Potential effects of co-administration of drugs that are highly bound to plasma proteins. Sertlin may interact with drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.
Contraindications
Contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of the drug. Not recommended in patients with moderate to severe hepatic impairment.
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
Safety during human pregnancy has not been established. Excreted in breast milk. Discontinuation of breast-feeding should be considered if treatment with Sertraline is considered necessary.
Precautions & Warnings
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Any allergies
- Dizziness or drowsiness
- Caution while using in the elderly
- Risk of suicidal thinking and change of behavior
- Do not take if taken monoamine oxidase inhibitor in the last five weeks
Therapeutic Class
SSRIs & related anti-depressant drugs
Storage Conditions
Do not store above 30°C. Keep out of the reach of children.