Ursodil 300 mg (Tablet)

Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)

Strip Price: ৳ 250.00

Medicine Details

Category	Details
Generic	Ursodeoxycholic acid
Company	General pharmaceuticals ltd
Also available as	Ursodil 150 mg tablet

Indications

Cholestasis (Jaundice)
Viral Hepatitis
Alcoholic Fatty Liver
Primary Billiary Cirrhosis (PBC)
Primary Sclerosing Cholangitis (PSC)
Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis (NASH)

Description

Reduces cholesterol saturation of bile and promotes dissolution of gallstones. Reduces cholesterol of secretion into bile, increases bile acid secretion rate.

Pharmacology

Decrease in secretion of cholesterol in bile
Reduces cholesterol absorption
Suppresses liver cholesterol synthesis
Promotes formation of liquid cholesterol crystal complexes
Completely absorbed in the upper intestine
Time to peak serum concentration varies from 30 to 150 minutes

Dosage & Administration

Dissolution of Gall stones: 8-12 mg/kg/day
Primary Billiary Cirrhosis: 10-15 mg/kg/day in 2-4 divided doses
Acute Viral Hepatitis: 600 mg/day
Alcoholic Fatty Liver: 300 mg/day
Primary Sclerosing Cholangitis: 25-30 mg/kg/day
Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day

Interaction

Avoid concomitant administration with drugs such as oestrogenic hormones or bile-acid binding drugs including antacids, charcoal, and cholestyramine.

Contraindications

Non-functioning gall-bladder
Calcified and pigmented gallstones
Inflammatory bowel disease

Side Effects

Nausea
Vomiting
Diarrhoea
Gallstone opacilication
Pruritus

Pregnancy & Lactation

Pregnancy category B. No evidence of harm reported. Effectively used for treatment of cholestasis of pregnancy during the last trimester. No documented problems regarding breastfeeding.

Precautions & Warnings

Use cautiously in those with liver disease.

Therapeutic Class

Anti-gallstones drugs: Bile Acids

Storage Conditions

Store below 25° C. Protected from light and moisture. Keep out of the reach of children.