Burnrid 1% (Cream)
25 gm tube: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Silver sulfadiazine |
| Company | Globe pharmaceuticals ltd |
Indications
- Prophylaxis against bacterial colonization in burn wounds
- Antibacterial management of contaminated wounds
Pharmacology
- Silver Sulfadiazine mechanism of action
- Structural changes in bacterial cell membrane
- Weakening of cell wall membrane
- Reduction in viability of sensitive strains
- Binding of silver moiety to bacterial cells
- Inactivation of bacterial cell proliferation
- Bacteriostatic action against sensitive organisms
- Absorption and excretion in adults and children
Dosage & Administration
- Cleansing of burn wounds before application
- Application thickness and frequency
- Reapplication after patient activity or hydrotherapy
- Use of dressings if necessary
- Duration of treatment and conditions for withdrawal
Interaction
- Inactivation of enzymatic debriding agents
- Potentiation of oral hypoglycemic agents and phenytoin
- Impact of co-administration of Cimetidine
Contraindications
- Hypersensitivity to the ingredients
- Use on pregnant women, premature infants, or newborns
Side Effects
- Transient leukopenia
- Skin necrosis
- Erythema multiform
- Skin discoloration
- Burning sensation
- Rashes
- Interstitial nephritis
Pregnancy & Lactation
- Pregnancy Category B classification
- Use during pregnancy if clearly justified
- Excretion in human milk
- Consideration for nursing mothers
Precautions & Warnings
- Monitoring hepatic and renal functions
- Possibility of inactivation of proteolytic enzymes
- Monitoring serum sulfa concentrations
- Renal function and urine checks
Therapeutic Class
- Topical Antibiotic preparations
Storage Conditions
- Temperature, light, and moisture requirements
- Keep out of reach of children