Simvatin 20 mg (Tablet)

Unit Price: ৳ 18.11 (1 x 10: ৳ 181.10)
Strip Price: ৳ 181.10

Medicine Details

Category Details
Generic Simvastatin
Company Acme laboratories ltd
Also available as

Indications

  • Primary hypercholesterolemia treatment
  • Coronary heart disease treatment

Pharmacology

  • Cholesterol lowering mechanism
  • LDL cholesterol reduction
  • VLDL cholesterol reduction
  • Liver metabolism

Dosage & Administration

  • Recommended starting dose
  • Maximum daily dose
  • Effect on LDL-cholesterol levels
  • Dosing range
  • Renal insufficiency considerations
  • Safety and effectiveness in children and adolescents

Interactions

  • Digoxin interaction
  • Coumarin derivatives interaction
  • Concomitant use with ACE inhibitors, beta-blockers, calcium channel blockers, diuretics, and NSAIDs

Contraindications

  • Active liver disease
  • Pregnancy and breastfeeding
  • Hypersensitivity
  • Homozygous familial hypercholesterolemia

Side Effects

  • Headache
  • Fatigue
  • Insomnia
  • Nausea
  • Constipation
  • Diarrhea
  • Flatulence
  • Dyspepsia
  • Abdominal cramps
  • Myalgia
  • Myositis
  • Myopathy
  • Rhabdomyolysis
  • Acute renal failure
  • Hepatitis
  • Pancreatitis
  • Rash
  • Angio-oedema

Pregnancy & Lactation

  • Category X
  • Contraindicated in pregnancy

Precautions & Warnings

  • History of liver disease
  • High alcohol consumption
  • Liver function test monitoring
  • Serum transaminase threshold
  • Avoiding pregnancy during and after treatment

Overdose Effects

  • No available data
  • No antidote available
  • General measures and liver function monitoring

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Cool and dry storage
  • Protected from light
  • Keep out of reach of children

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