Sucosit 50 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Monotherapy and Combination Therapy
- Improving glycemic control in adults with type 2 diabetes mellitus
- Not for use in patients with type 1 diabetes
- Not effective for the treatment of diabetic ketoacidosis
Pharmacology
- DPP-4 inhibitor
- Slows inactivation of incretin hormones
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
- Increases insulin release and decreases glucagon levels
Dosage & Administration
- Recommended dose of 50mg twice a day or 100mg once daily
- Can be taken with or without food
Interaction
- Does not meaningfully alter the pharmacokinetics of specific drugs
- Slightly increases the mean concentration of Digoxin
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia may occur in certain patients
Pregnancy & Lactation
- Pregnancy Category B
- Secreted in the milk of lactating rats
- Caution advised when administered to a nursing woman
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment recommended in patients with renal insufficiency
- Caution advised when used with medications known to cause hypoglycemia
- Reports of serious hypersensitivity reactions
- Safety and effectiveness not established in pediatric patients under 18 years of age
Use in Special Populations
- Substantial excretion by the kidney in elderly patients
- Different dosage adjustments for patients with renal insufficiency
- Not established for pediatric patients under 18 years of age
Overdose Effects
- Maximal mean increase in QTc observed in controlled clinical trials
- Employ supportive measures in the event of an overdose
- Modestly dialyzable
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of the reach of children
- Do not use later than the date of expiry