SB-Sita 50 mg (Tablet)
Unit Price: ৳ 15.00 (20's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Sunman birdem pharma ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for adults with type 2 diabetes mellitus
- Not for use in patients with type 1 diabetes
- Not for the treatment of diabetic ketoacidosis
- Not studied in patients with a history of pancreatitis
Pharmacology
- DPP-4 inhibitor
- Slows inactivation of incretin hormones
- Increases and prolongs action of incretin hormones
- Regulates glucose homeostasis
- Increases insulin release and decreases glucagon levels
- Selective for DPP-4
Dosage & Administration
- 50 mg twice a day
- 100 mg once daily
- Can be taken with or without food
Interaction
- No meaningful alteration of pharmacokinetics of other drugs
- Slight increase in mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Headache
- Upper respiratory tract infection
- Nasopharyngitis
- Hypoglycemia may occur in combination with sulfonylurea or insulin
Pregnancy & Lactation
- Pregnancy Category B
- Caution advised during lactation
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in renal insufficiency
- Caution with medications known to cause hypoglycemia
- Risk of hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients under 18 years of age
- Dose adjustment in elderly patients with decreased renal function
Overdose Effects
- Modestly dialyzable
- Usual supportive measures in case of overdose
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C
- Keep away from light
- Keep out of the reach of children
- Use before expiry date
- To be dispensed only on prescription