Sitazid M 50 mg+500 mg (Tablet)

Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Sitagliptin metformin hydrochloride
Company Eskayef pharmaceuticals ltd
Also available as
Sitazid m 50 mg tablet

Title

  • Oral Diabetes Medication

Categories

  • Medicine
  • Health
  • Diabetes Care

Description

  • Combines two antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes.

Dimensions

  • Film-coated tablet
  • Extended-release tablet

Color Options

  • None

Functions

  • Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
  • Decreases hepatic glucose production
  • Decreases intestinal absorption of glucose
  • Increases peripheral glucose uptake and utilization

Materials

  • Sitagliptin
  • Metformin HCl

Technical Specifications

  • Maximum recommended daily dose of 100 mg sitagliptin and 2000 mg metformin
  • Administered twice daily with meals
  • Individualized dosage based on patient's current regimen
  • Cautious use with cationic drugs eliminated by renal tubular secretion

Design Elements

  • Film-coated tablet
  • Extended-release tablet

Usability Features

  • Individualized dose escalation to reduce gastrointestinal side effects due to metformin
  • Temporary discontinuation in patients undergoing radiologic studies involving intravascular administration of iodinated contrast materials

Interactions

  • Cationic drugs - use with caution
  • Possible influence on phenprocoumon and levothyroxine effectiveness

Contraindications

  • Renal disease or dysfunction
  • Acute or chronic metabolic acidosis
  • History of serious hypersensitivity reactions
  • Use during radiologic studies involving iodinated contrast materials

Side Effects

  • Diarrhea
  • Upper respiratory tract infection
  • Headache
  • Hypoglycemia
  • Nasopharyngitis
  • Nausea/vomiting
  • Flatulence
  • Abdominal discomfort
  • Indigestion
  • Asthenia

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during lactation

Precautions & Warnings

  • Lactic Acidosis risk
  • Regular monitoring of thyroid-stimulating hormone (TSH) levels
  • Long-term treatment associated with decrease in vitamin B12 serum levels
  • Postmarketing reports of acute renal failure and pancreatitis
  • Hematologic parameters monitoring
  • Caution against excessive alcohol intake
  • Potential allergic and hypersensitivity reactions
  • No conclusive evidence of macrovascular risk reduction

Overdose Effects

  • Supportive measures in case of overdose
  • Dialyzable in case of overdose

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Store below 25°C in a dry place away from light
  • Keep out of reach of children
  • Do not use after expiry date

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