Sitadus-M 50 mg+500 mg (Tablet (Extended Release))

Unit Price: ৳ 16.00 (2 x 10: ৳ 320.00)
Strip Price: ৳ 160.00

Medicine Details

Category Details
Generic Sitagliptin metformin hydrochloride
Company Opsonin pharma ltd
Also available as
Sitadus m 50 mg tablet

Title

Sitagliptin and Metformin Tablet

Categories

  • Medicine
  • Diabetes management
  • Oral hypoglycemic

Description

A tablet indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both sitagliptin and metformin is appropriate.

Color Options

  • White

Dosage Form

Film-coated tablet, extended-release tablet

Dosage Strengths

  • 50 mg sitagliptin/500 mg metformin
  • 50 mg sitagliptin/1000 mg metformin
  • 100 mg sitagliptin/1000 mg metformin

Administration

  • Twice daily with meals
  • Administer once daily with a meal

Maximum Daily Dose

100 mg sitagliptin and 2000 mg metformin

Interaction with Drugs

  • Cationic Drugs: Use with caution
  • Phenprocoumon: Metformin may decrease the anticoagulant effect
  • Levothyroxine: May reduce the hypoglycemic effect of metformin

Contraindications

  • Renal disease or dysfunction
  • Metabolic acidosis
  • History of serious hypersensitivity reaction

Side Effects

  • Diarrhea
  • Upper respiratory tract infection
  • Headache
  • Hypoglycemia
  • Nasopharyngitis
  • Nausea/vomiting
  • Fatulence
  • Abdominal discomfort
  • Indigestion
  • Asthenia

Pregnancy Category

Category B

Precautions & Warnings

  • Lactic Acidosis risk
  • Regular monitoring of TSH levels is recommended
  • Monitoring of vitamin B12 level is recommended
  • Renal function assessment is advised

Overdose Effects

  • Sitagliptin: It is reasonable to employ the usual supportive measures
  • Metformin Hydrochloride: Hemodialysis may be useful for removal of accumulated drug

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage

  • Conditions: Store below 25°C in a dry place away from light
  • Caution: Keep the medicines in a safe place, out of the reach of children

Limitations of Use

  • Not suitable for type 1 diabetes or diabetic ketoacidosis

Pharmacology

Combines two antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes

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