Centoxin 0.25 mg/5 ml (Oral Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Digoxin |
| Company | Opsonin pharma ltd |
| Also available as |
Product Title
- Centoxin
Categories
- Medicine
- Cardiology
- Pharmacology
- Therapeutic Class
Description
Centoxin is indicated in heart failure, atrial fibrillation with an uncontrolled ventricular rate, acute left ventricular failure, chronic left ventricular failure, and congestive heart failure caused by hypertensive valvular or ischaemic heart disease. It is a cardiac glycoside used in the management of atrial fibrillation and heart failure. The principal actions of digoxin are an increase in the force of myocardial contraction and a reduction in the conductivity of the heart. It is administered orally, and the dosage varies based on the urgency and individual patient factors. Centoxin has interactions with various medications and contraindications in cases of ventricular fibrillation and hypersensitivity to digoxin or other digitalis preparations. Side effects may include anorexia, nausea, vomiting, visual disturbance, fatigue, confusion, arrhythmia, and others. It can be used in pregnancy and excreted in breast milk at low concentrations. It can be used in neonates, children, and the elderly, with the latter requiring a lower maintenance dose. Centoxin belongs to the therapeutic class of Positive Inotropic drugs and should be stored in a cool and dry place, out of the reach of children.
Dimensions
Color Options
Functions
- Management of atrial fibrillation
- Management of heart failure
- Positive inotropic activity
- Reduction in the conductivity of the heart
- Direct action on vascular smooth muscle
- Increase in vagal activity
Materials
Technical Specifications
- Dosage for rapid digitalization
- Dosage for less urgent digitalization
- Maintenance dosage
- Usual dosage range
- Interactions with potassium-depleting diuretics
- Interactions with calcium
- Interactions with various medications
- Contraindications for ventricular fibrillation and hypersensitivity
- Excretion in breast milk
- Use in neonates, children, and the elderly
Design Elements
Usability Features
- Oral administration
- Storage in a cool and dry place
- Keep out of the reach of children
Indications
- Heart failure
- Atrial fibrillation
Pharmacology
- Increase in force of myocardial contraction
- Reduction in conductivity of the heart
- Direct action on vascular smooth muscle
- Indirect effects mediated by the autonomic nervous system
Dosage & Administration
- Rapid digitalization dosage
- Less urgent digitalization dosage
- Maintenance dosage
- Usual dosage range
- Oral administration
Interaction
- Potassium-depleting diuretics interaction
- Calcium interaction
- Interactions with various medications
Contraindications
- Ventricular fibrillation
- Hypersensitivity to digoxin
Side Effects
- Anorexia
- Nausea
- Vomiting
- Visual disturbance
- Fatigue
- Confusion
- Arrhythmia
- Gynaecomastia
- Thrombocytopenia
Pregnancy & Lactation
- Excretion in breast milk
- Safe use in pregnancy
Use in Special Populations
- Use in neonates
- Use in children
- Lower maintenance dose for the elderly
Therapeutic Class
- Positive Inotropic drugs
Storage Conditions
- Cool and dry place
- Keep out of the reach of children