Valepi 200 mg (Tablet)

Unit Price: ৳ 6.20 (5 x 10: ৳ 310.00)
Strip Price: ৳ 62.00

Medicine Details

Category Details
Generic Sodium valproate
Company Medimet pharmaceuticals ltd

Indications

  • Treatment of epilepsy
  • Treatment of partial seizures
  • Treatment of absence seizures
  • Treatment of generalized tonic-clonic seizures
  • Treatment of myoclonic seizures
  • Treatment of atonic seizures
  • Treatment of mixed seizures
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet 200 mg
  • Sodium Valproate syrup 200 mg/5ml
  • Sodium Valproate controlled release 200 tablet
  • Sodium Valproate controlled release 300 tablet
  • Sodium Valproate controlled release 500 tablet
  • Sodium Valproate injection 500 mg/5ml

Pharmacology

  • Endowed with anti-epileptic activity
  • Increases brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration
  • Initial dose for adults 600 mg daily
  • Usual maintenance dose 1-2 g daily
  • Initial dose for children over 20 kg 400 mg daily
  • Usual maintenance dose for children up to 20 kg 20 mg/kg daily
  • Prophylaxis of migraine dose 400-600 mg daily
  • Injection for adults 400-800 mg slow intravenous injection
  • Injection for children initial dose 20-30 mg/kg/day

Interaction

  • Non specific inhibitor of drug metabolism
  • Significant interaction with Phenobarbital
  • Significant interaction with Phenytoin
  • Significant interaction with Warfarin
  • Significant interaction with Aspirin

Contraindications

  • Known hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy
  • Restricted use in women of childbearing potential

Side Effects

  • Anorexia
  • Nausea
  • Vomiting
  • Sedation
  • Ataxia
  • Tremor
  • Rash
  • Alopecia
  • Stimulation of appetite
  • Elevation of liver enzymes
  • Fulminate hepatitis
  • Acute pancreatitis
  • Hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborn
  • Excreted in breast milk

Precautions & Warnings

  • Monitor liver functions
  • Ensure no undue potential for bleeding
  • Take care in renal impairment
  • Avoid sudden withdrawal of therapy
  • Avoid use during pregnancy
  • Avoid use in women of childbearing potential

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

Related Brands