Valepi 200 mg (Tablet)
Unit Price: ৳ 6.20 (5 x 10: ৳ 310.00)
Strip Price: ৳ 62.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium valproate |
| Company | Medimet pharmaceuticals ltd |
Indications
- Treatment of epilepsy
- Treatment of partial seizures
- Treatment of absence seizures
- Treatment of generalized tonic-clonic seizures
- Treatment of myoclonic seizures
- Treatment of atonic seizures
- Treatment of mixed seizures
- Prophylaxis of febrile convulsion
- Prophylaxis of post-traumatic epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
Composition
- Sodium Valproate tablet 200 mg
- Sodium Valproate syrup 200 mg/5ml
- Sodium Valproate controlled release 200 tablet
- Sodium Valproate controlled release 300 tablet
- Sodium Valproate controlled release 500 tablet
- Sodium Valproate injection 500 mg/5ml
Pharmacology
- Endowed with anti-epileptic activity
- Increases brain levels of gamma-aminobutyric acid (GABA)
Dosage & Administration
- Oral administration
- Initial dose for adults 600 mg daily
- Usual maintenance dose 1-2 g daily
- Initial dose for children over 20 kg 400 mg daily
- Usual maintenance dose for children up to 20 kg 20 mg/kg daily
- Prophylaxis of migraine dose 400-600 mg daily
- Injection for adults 400-800 mg slow intravenous injection
- Injection for children initial dose 20-30 mg/kg/day
Interaction
- Non specific inhibitor of drug metabolism
- Significant interaction with Phenobarbital
- Significant interaction with Phenytoin
- Significant interaction with Warfarin
- Significant interaction with Aspirin
Contraindications
- Known hypersensitivity to the drug
- Liver dysfunction
- Restricted use during pregnancy
- Restricted use in women of childbearing potential
Side Effects
- Anorexia
- Nausea
- Vomiting
- Sedation
- Ataxia
- Tremor
- Rash
- Alopecia
- Stimulation of appetite
- Elevation of liver enzymes
- Fulminate hepatitis
- Acute pancreatitis
- Hyperammonemia
Pregnancy & Lactation
- Crosses the placenta
- Associated with neural tube defects in newborn
- Excreted in breast milk
Precautions & Warnings
- Monitor liver functions
- Ensure no undue potential for bleeding
- Take care in renal impairment
- Avoid sudden withdrawal of therapy
- Avoid use during pregnancy
- Avoid use in women of childbearing potential
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children
Related Brands
- Valex 500 mg/5 ml (IV Injection) - incepta-pharmaceuticals-ltd
- Sodival CR 500 mg (Tablet (Controlled Release)) - aci-limited
- Valporin CR 200 mg (Tablet (Controlled Release)) - renata-limited
- Valporin CR 300 mg (Tablet (Controlled Release)) - renata-limited
- Valporin CR 500 mg (Tablet (Controlled Release)) - renata-limited