Convules CR 200 mg (Tablet (Controlled Release))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium valproate |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of all types of epilepsy
- Prophylaxis of febrile convulsion
- Prophylaxis of post-traumatic epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
Composition
- Sodium Valproate tablet: Each enteric-coated tablet contains Sodium Valproate BP 200 mg
- Sodium Valproate syrup: Each 5 ml syrup contains Sodium Valproate BP 200 mg
- Sodium Valproate controlled release 200 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 200 mg as Sodium Valproate BP 133.2 mg & Valproic acid BP 58 mg
- Sodium Valproate controlled release 300 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 300 mg as Sodium Valproate BP 199.8 mg & Valproic acid BP 87 mg
- Sodium Valproate controlled release 500 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 500 mg as Sodium Valproate BP 333 mg & Valproic acid BP 145 mg
- Sodium Valproate injection: Each 5 ml injectable solution contains Sodium Valproate BP eqv. to Valproic Acid 500 mg
Pharmacology
- Sodium Valproate has anti-epileptic activity against a variety of seizures
- Increase in brain levels of gamma-aminobutyric acid (GABA)
Dosage & Administration
- Oral administration for epilepsy treatment in adults and children
- Dosage for prophylaxis of migraine
- Injection dosage for adults and children
Interaction
- Inhibitor of drug metabolism
- Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin
Contraindications
- Hypersensitivity to the drug
- Liver dysfunction
- Restricted use during pregnancy and in women of childbearing potential
Side Effects
- Anorexia
- Nausea
- Vomiting
- Sedation
- Ataxia
- Tremor
- Rash
- Alopecia
- Stimulation of appetite
- Elevation of liver enzymes
- Hepatic injury
- Acute pancreatitis
- Hyperammonemia
Pregnancy & Lactation
- Crosses the placenta
- Associated with neural tube defects in newborns
- Excreted in breast milk
Precautions & Warnings
- Monitoring of liver functions
- No undue potential for bleeding
- Care in renal impairment, pregnancy, breast-feeding, systemic lupus erythematosus
- Eliminated in the urine as a ketone metabolite
- Avoid sudden withdrawal of therapy
- Not to be used during pregnancy and in women of childbearing potential
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children
Related Brands
- Valex 500 mg/5 ml (IV Injection) - incepta-pharmaceuticals-ltd
- Sodival CR 500 mg (Tablet (Controlled Release)) - aci-limited
- Valporin CR 200 mg (Tablet (Controlled Release)) - renata-limited
- Valporin CR 300 mg (Tablet (Controlled Release)) - renata-limited
- Valporin CR 500 mg (Tablet (Controlled Release)) - renata-limited