Convules CR 200 mg (Tablet (Controlled Release))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Sodium valproate
Company Opsonin pharma ltd
Also available as
Convules 200 mg syrup Convules cr 300 mg tablet Convules cr 500 mg tablet

Indications

  • Treatment of all types of epilepsy
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet: Each enteric-coated tablet contains Sodium Valproate BP 200 mg
  • Sodium Valproate syrup: Each 5 ml syrup contains Sodium Valproate BP 200 mg
  • Sodium Valproate controlled release 200 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 200 mg as Sodium Valproate BP 133.2 mg & Valproic acid BP 58 mg
  • Sodium Valproate controlled release 300 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 300 mg as Sodium Valproate BP 199.8 mg & Valproic acid BP 87 mg
  • Sodium Valproate controlled release 500 tablet: Each enteric-coated controlled release tablet contains Sodium Valproate 500 mg as Sodium Valproate BP 333 mg & Valproic acid BP 145 mg
  • Sodium Valproate injection: Each 5 ml injectable solution contains Sodium Valproate BP eqv. to Valproic Acid 500 mg

Pharmacology

  • Sodium Valproate has anti-epileptic activity against a variety of seizures
  • Increase in brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration for epilepsy treatment in adults and children
  • Dosage for prophylaxis of migraine
  • Injection dosage for adults and children

Interaction

  • Inhibitor of drug metabolism
  • Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy and in women of childbearing potential

Side Effects

  • Anorexia
  • Nausea
  • Vomiting
  • Sedation
  • Ataxia
  • Tremor
  • Rash
  • Alopecia
  • Stimulation of appetite
  • Elevation of liver enzymes
  • Hepatic injury
  • Acute pancreatitis
  • Hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborns
  • Excreted in breast milk

Precautions & Warnings

  • Monitoring of liver functions
  • No undue potential for bleeding
  • Care in renal impairment, pregnancy, breast-feeding, systemic lupus erythematosus
  • Eliminated in the urine as a ketone metabolite
  • Avoid sudden withdrawal of therapy
  • Not to be used during pregnancy and in women of childbearing potential

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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